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Bioabsorbable, biobeneficial polyester polymers for stent coatings

  • US 7,301,001 B2
  • Filed: 12/20/2006
  • Issued: 11/27/2007
  • Est. Priority Date: 06/11/2003
  • Status: Expired due to Fees
First Claim
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1. A polymer comprising:

  • a) an alcoholic moiety derived from an aliphatic diol, triol, or polyol;

    b) an acidic moiety derived from a polcarboxylic acid; and

    c) a biobeneficial moiety derived from polypropylene glycol, PLURONIC™

    surfactants, block copolymers comprising polyethylene glycol and polypropylene glycol, hydroxy functional poly(vinyl pyrrolidone), dextrin, sodium hyaluronate, hyaluronic acid, elastin, water-soluble heparin, water-soluble elastin, tropoelastin, poly(2-hydroxyethyl methylmethacrylate), heparin, hirudin, sulfonated polystyrene, superoxide dismutase mimetics, anti-oxidants, or free radical scavengers,wherein the polycarboxylic acid is selected from the acidic moiety derived from at least one diacid selected from the group consisting of straight chain aliphatic diacids having 2 to 20 carbon atoms, terephthalic acid, fumaric acid, citric acid, citramalic acid, tricarballylic acid, tartaric acid, isophthalic acid, 1,6-bis(p-carboxy phenoxy)hexane, 1,3-bis(p-phenoxy carboxy)propane, 1,4-bis(p-phenoxy carboxy)butane, and oligomeric diacids with anhydride bonds in the backbone.

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