Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma
First Claim
1. A disposable centrifuge apparatus comprising:
- a separation chamber consisting essentially of a first chamber section and a second chamber section, separated by a divider element with each chamber section including a cylindrical elongated portion adjacent to the divider element, a collection portion with a side wall that slopes inward toward the central axis of the chamber section to define a reducing circular cross-section along the central axis, a cylindrical nipple attached to the collection portion, and a port providing an inlet and an outlet path for fluid to the chamber section; and
a tubing assembly including first and second tubing sections attached to the chamber section ports at a first end and a three-way tubing connector connecting second ends of the first and second tubing sections, wherein the tubing assembly is shaped substantially as an arc;
a third tubing section having a first end and a second end, wherein the first end is attached to the three-way tubing connector;
a fourth tubing section having a first end and a second end; and
a tube clamp connecting the second end of the third tubing section and the first end of the fourth tubing section, wherein the clamp comprises a tapered section;
wherein the first, second and third tubing sections of the tubing assembly form a loop and are in fluid communication with each other and the separation chamber.
8 Assignments
0 Petitions
Accused Products
Abstract
A centrifugal method, and corresponding system, for processing blood to collect platelet rich plasma. A separation chamber is filled with blood from a fill syringe by rotating the separation chamber at a fill rotation rate and pumping the blood from the fill syringe. A soft spin is used to initially separate red blood cells from platelets by spinning the separation chamber at a soft spin rate. A percentage of the blood is drawn from the separation chamber back into the fill syringe to remove separated red blood cells. A second portion of the separated blood is drawn from the separation chamber until a red blood cell/platelet interface is detected. A hard spin is performed by spinning the separation chamber at a higher rate and connecting tubing is cleared of red blood cells by drawing a predetermined clearing volume. The platelet rich plasma is then collected in the collection syringe.
-
Citations
10 Claims
-
1. A disposable centrifuge apparatus comprising:
-
a separation chamber consisting essentially of a first chamber section and a second chamber section, separated by a divider element with each chamber section including a cylindrical elongated portion adjacent to the divider element, a collection portion with a side wall that slopes inward toward the central axis of the chamber section to define a reducing circular cross-section along the central axis, a cylindrical nipple attached to the collection portion, and a port providing an inlet and an outlet path for fluid to the chamber section; and a tubing assembly including first and second tubing sections attached to the chamber section ports at a first end and a three-way tubing connector connecting second ends of the first and second tubing sections, wherein the tubing assembly is shaped substantially as an arc; a third tubing section having a first end and a second end, wherein the first end is attached to the three-way tubing connector; a fourth tubing section having a first end and a second end; and a tube clamp connecting the second end of the third tubing section and the first end of the fourth tubing section, wherein the clamp comprises a tapered section; wherein the first, second and third tubing sections of the tubing assembly form a loop and are in fluid communication with each other and the separation chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
-
Specification