Method to monitor progression of atrial fibrillation and to detect its susceptibility for termination

• US 7,308,308 B1
• Filed: 04/25/2005
• Issued: 12/11/2007
• Est. Priority Date: 09/16/2004
• Status: Expired due to Fees

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Xi, Cecilia Qin, Shkurovich, Sergio
• Primary Examiner(s): Schaetzle, Kennedy J.
• Assistant Examiner(s): Patel, Natasha
• Application Number:
  US11/114,799
• Time in Patent Office: 960 Days
• Field of Search: 607 3- 6, 607/9, 607/14, 607/17, 607/28
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

A method and apparatus for monitoring a patient'"'"'s cardiac electrical activity is disclosed. The method includes determining a characteristic of the cardiac signals during a detected episode of atrial fibrillation. The method further includes comparing the characteristic to an atrial fibrillation therapy threshold and if the characteristic is less than or equal to the atrial fibrillation therapy threshold further comparing the characteristic to a self-termination threshold. If the characteristic is less than the self-termination threshold the method withholds anti-tachycardia therapy to allow the arrhythmia to self-terminate.

Claims

1. A method for processing a patient'"'"'s cardiac signals, comprising:

detecting an ongoing episode of atrial fibrillation;

determining a characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation;

comparing the characteristic to an atrial fibrillation therapy threshold;

comparing the characteristic to a self-termination threshold if the characteristic is less than or equal to the atrial fibrillation therapy threshold; and

withholding anti-tachycardia therapy if the characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation is less than the self-termination threshold.

2. The method of claim 1 further comprising delivering anti-tachycardia therapy if the characteristic is greater than or equal to the self-termination threshold.

3. The method of claim 1 wherein determining a characteristic of the cardiac signals comprises determining cardiac heart rate.

4. The method of claim 1 wherein determining a characteristic of the cardiac signals comprises determining peak frequency of the cardiac signals.

5. The method of claim 4 further comprising canceling a QRST segment of the cardiac signals.

6. The method of claim 1 further comprising determining whether the patient returned to sinus rhythm in response to delivery of the anti-tachycardia therapy.

8. The method of claim 2 further comprising determining whether the patient returned to sinus rhythm in response to with-holding delivery of the anti-tachycardia therapy.

11. The method of claim 6 further comprising activating an implantable drug pump to administer an anti-tachycardia drug if the patient does not return to sinus rhythm.

12. The method of claim 1 further comprising generating the atrial fibrillation therapy threshold and the self-termination threshold from a database of cardiac signals.

15. The method of claim 1 further comprising monitoring the characteristic of the cardiac signals to determine if the characteristic is less than or equal to the atrial fibrillation therapy threshold for a predetermined period, wherein comparing the characteristic to the self-termination threshold comprises comparing the characteristic to the self termination threshold if the characteristic is less than or equal to atrial fibrillation therapy threshold for a predetermined period.

7. The method 6 further comprising updating an atrial fibrillation progression histogram to monitor progression of the atrial fibrillation.

13. The method of claim 7 further comprising adjusting at least one of the atrial fibrillation therapy threshold and the self-termination threshold in response to data stored in the atrial fibrillation progression histogram.

9. The method 8 further comprising updating an atrial fibrillation progression histogram to monitor progression of the atrial fibrillation.

10. The method of claim 9 wherein updating an atrial fibrillation progression histogram comprises storing termination mechanism and characteristic of cardiac signal at termination.

14. The method of claim 9 further comprising adjusting at least one of the atrial fibrillation therapy threshold and the self-termination threshold as a function of data stored in the atrial fibrillation progression histogram.

16. A medical device for monitoring a patient'"'"'s cardiac signals, comprising:

means for detecting an ongoing episode of atrial fibrillation;

means for determining a characteristic of the cardiac signals sensed during the ongoing atrial fibrillation episode;

means for comparing the characteristic to an atrial fibrillation therapy threshold;

means for comparing the characteristic to a self-termination threshold if the characteristic is less than or equal to the atrial fibrillation therapy threshold; and

means for with-holding anti-tachycardia therapy if the characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation is less than the self-termination threshold.

17. The device of claim 16 further comprising means for monitoring the characteristic of the cardiac signals to determine if the characteristic is less than or equal to the atrial fibrillation therapy threshold for a predetermined period, wherein the means for comparing the characteristic to the self-termination threshold comprises means for comparing the characteristic to the self termination threshold if the characteristic is less than or equal to atrial fibrillation therapy threshold for a predetermined period.

18. The device of claim 16 further comprising means for delivering anti-tachycardia therapy if the characteristic is greater than or equal to the self-termination threshold.

19. The device of claim 16 wherein the means for determining a characteristic of the cardiac signals comprises means for determining cardiac heart rate.

20. The device of claim 16 wherein the means for determining a characteristic of the cardiac signals comprises means for determining peak frequency of the cardiac signals.

21. A medical device for monitoring a patient'"'"'s cardiac signals, comprising:

a rhythm detector for detecting an ongoing episode of atrial fibrillation;

sensor for determining a characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation; and

a controller coupled to the sensor, the controller being adapted to compare the characteristic to a atrial fibrillation therapy threshold and if the characteristic is less than or equal to the atrial fibrillation therapy threshold for further comparing the characteristic to a self termination threshold and wherein the controller with-holds delivery of anti-tachycardia therapy if the characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation is less than the self-termination threshold.

22. The device of claim 21 further comprising an atrial pulse generator for delivering anti-tachycardia therapy if the characteristic is greater than or equal to the self-termination threshold.

23. A method for processing a patient'"'"'s cardiac signals, comprising:

detecting an ongoing episode of atrial fibrillation;

determining a characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation;

comparing the characteristic to an atrial fibrillation therapy threshold; and

withholding therapy if the characteristic of the cardiac signals sensed during the ongoing episode of atrial fibrillation is greater than the atrial fibrillation therapy threshold.

24. The method of claim 23 further comprising comparing the characteristic to a self-termination threshold if the characteristic is less than or equal to the atrial fibrillation therapy threshold and withholding anti-tachycardia therapy if the characteristic is less than the self-termination threshold.

25. The method of claim 24 further comprising delivering anti-tachycardia therapy if the characteristic is greater than or equal to the self-termination threshold and less than or equal to the atrial fibrillation therapy threshold.