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Method for predicting apnea-hypopnea index from overnight pulse oximetry readings

  • US 7,309,314 B2
  • Filed: 09/23/2004
  • Issued: 12/18/2007
  • Est. Priority Date: 09/23/2003
  • Status: Expired due to Fees
First Claim
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1. A method for predicting respiratory disturbances in an individual comprising the steps of:

  • a) identifying patients having obstructive sleep apnea;

    b) determining actual Apopnea Hypopnea Index (AHI) in the patients;

    c) obtaining pulse oximetry recordings from the patients;

    d) determining patient data comprising a set of indices from the pulse oximetry readings comprising;

    delta index, time spent at selected oxygen saturation levels and oxygen desaturation events;

    e) performing random sampling with replacement of patient data from (d) to generate a plurality of data sets;

    f) performing multivariate non-parametric analysis in the plurality of data sets to generate a plurality of prediction models;

    g) obtaining a provisional predictive AHI value for each patient corresponding to each prediction model;

    h) comparing the provisional predictive AHI value to actual AHI value for each patient to provide weight to each prediction model; and

    i) providing each prediction model to a health care professional,wherein the plurality of prediction models and weight of the prediction models provides a predictive tool for predicting respiratory disturbances in an individual.

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