Silicon microprobe with integrated biosensor
First Claim
Patent Images
1. A microprobe device for providing a signal to an external analyte meter indicating analyte presence in an analyte-containing bodily fluid of a subject, the microprobe device comprising:
- a silicon substrate having an X length dimension and a Y width dimension and a Z thickness dimension, and having front side and a back side extending in the X and Y dimensions;
a body portion formed by the silicon substrate;
a microprobe portion formed by the silicon substrate, having a body end connected to the body portion, and having a penetration end extending away from the body portion in the X length dimension for penetrating into the subject to access the fluids; and
a biosensor integrated into the silicon substrate, for sensing analyte presence and for providing a signal in response to the analyte presence; and
a silicon microfillet portion at the connection between the body end of the microprobe portion and the body portion.
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Abstract
Microprobe device 10 provides an analyte signal from biosensor 12 to an external analyte meter indicating analyte presence in an analyte-containing bodily fluid of a subject (not shown).
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Citations
42 Claims
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1. A microprobe device for providing a signal to an external analyte meter indicating analyte presence in an analyte-containing bodily fluid of a subject, the microprobe device comprising:
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a silicon substrate having an X length dimension and a Y width dimension and a Z thickness dimension, and having front side and a back side extending in the X and Y dimensions; a body portion formed by the silicon substrate;
a microprobe portion formed by the silicon substrate, having a body end connected to the body portion, and having a penetration end extending away from the body portion in the X length dimension for penetrating into the subject to access the fluids; anda biosensor integrated into the silicon substrate, for sensing analyte presence and for providing a signal in response to the analyte presence; and a silicon microfillet portion at the connection between the body end of the microprobe portion and the body portion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A microprobe device for providing a signal to an external analyte meter indicating analyte presence in an analyte-containing bodily fluid of a subject, comprising:
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a silicon substrate having an X length dimension and a Y width dimension and a Z thickness dimension, and having a front side and a back extending in the X and Y dimensions and a cavity extending into the silicon substrate in the Z thickness dimension a body portion formed by the silicon substrate; a microprobe portion formed by the silicon substrate, having a body end connected to the body portion, and having a penetration end extending away from the body portion in the X length dimension for penetrating into the subject to access the fluids; and a biosensor integrated into the silicon substrate, for sensing analyte presence and for providing a signal in response to the analyte presence, the biosensor being deposited onto the silicon within the cavity. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A microprobe device for providing a signal to an external analyte meter indicating analyte presence in an analyte-containing bodily fluid of a subject, comprising:
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a silicon substrate having an X length dimension and a Y width dimension and a Z thickness dimension, and having a front side and a back side extending in the X and Y dimensions; a body portion formed by the silicon substrate; a microprobe portion formed by the silicon substrate, having a body end connected to the body portion, and having a penetration end extending away from the body portion in the X length dimension for penetrating into the subject to access the fluids; and at least one biosensor integrated into each side of the silicon substrate, for sensing analyte presence and for providing a signal in response to the analyte presence. - View Dependent Claims (42)
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Specification