Multifunctional carrier for the delivery of a pharmacological agent or genetic material into a cell
First Claim
1. A molecular carrier comprising a central multivalent core and a plurality of adduct molecules bonded thereto, wherein the molecular carrier is represented by the formula:
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Abstract
The present invention provides a drug delivery vehicle that can improve the pharmacokinetics of pharmacological agents. The invention relates to a multifunctional carrier capable of delivering a carried material such as a pharmacological agent or genetic material to a recipient. The multifunctional carrier includes a multifunctional core and a plurality of adduct molecules bonded thereto. The molecular carrier has surface functional groups which can be associated with a carried material. The carried material can be associated with the molecular carrier through covalent interactions or ionic interactions. The polyvalent core can be ethylene-diamine tetraacetic acid (EDTA) or succinic acid. The invention also relates to methods for producing and using such molecules.
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Citations
2 Claims
- 1. A molecular carrier comprising a central multivalent core and a plurality of adduct molecules bonded thereto, wherein the molecular carrier is represented by the formula:
Specification
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- Resources
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Current AssigneeVaxim Incorporated
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Original AssigneeVaxim Incorporated
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InventorsZhu, Shuren, Li, Frank Q., Chu, Yong Liang, Qiu, Jian-Tai, Lai, Wan-Ching
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Primary Examiner(s)DAVIS, BRIAN J
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Application NumberUS10/137,355Publication NumberTime in Patent Office2,069 DaysField of SearchNoneUS Class Current564/153CPC Class CodesA61K 47/6949 inclusion complexes, e.g. c...A61K 48/00 Medicinal preparations cont...B82Y 5/00 Nanobiotechnology or nanome...C12N 15/87 Introduction of foreign gen...
