Continuous spectroscopic measurement of total hemoglobin
First Claim
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1. A method of determining total hemoglobin of whole blood to guide patient treatment, comprising:
- transmitting light at multiple wavelengths in the visible spectrum into whole blood;
receiving the light from the whole blood;
determining light absorbance of the light at each of the multiple wavelengths;
determining a change in the light absorbance of the light between the multiple wavelengths; and
determining total hemoglobin of the whole blood using the change in the light absorbance of the light between the multiple wavelengths in proportion to a difference between the wavelengths;
providing the total hemoglobin for patient treatment.
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Abstract
Methods for measuring the total hemoglobin of whole blood include measuring reflective light at multiple wavelengths within the visible spectrum, calculating light absorbance at each of the multiple wavelengths, performing a comparison in a change in like absorbance between the multiple wavelengths, and/or relating the comparison to total hemoglobin. A system for measuring total hemoglobin of whole blood may include at least one light source, a catheter, optical fibers, at least one photodetector, data processing circuitry, and/or a display unit.
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15 Claims
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1. A method of determining total hemoglobin of whole blood to guide patient treatment, comprising:
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transmitting light at multiple wavelengths in the visible spectrum into whole blood; receiving the light from the whole blood; determining light absorbance of the light at each of the multiple wavelengths; determining a change in the light absorbance of the light between the multiple wavelengths; and determining total hemoglobin of the whole blood using the change in the light absorbance of the light between the multiple wavelengths in proportion to a difference between the wavelengths; providing the total hemoglobin for patient treatment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. The method of claim further comprising relating the total hemoglobin of the whole blood to hematocrit.
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10. A method of determining total hemoglobin of whole blood to guide patient treatment, comprising:
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providing a light source configured to emit light at multiple wavelengths; measuring a reference signal containing a spectra of the light source; measuring a dark signal when the light source is off; measuring a remitted signal from whole blood when the light source is on; determining light absorbance from the reference signal and the remitted signal; and determining total hemoglobin of the whole blood based on a change in the light absorbance between the multiple wavelengths in proportion to a difference between the wavelengths; providing the total hemoglobin for patient treatment. - View Dependent Claims (11, 12, 13, 14, 15)
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