Medicant delivery system and method

• US 7,320,319 B2
• Filed: 11/17/2004
• Issued: 01/22/2008
• Est. Priority Date: 12/02/2000
• Status: Expired due to Fees

• Current Assignee: P TECH, LLC
• Original Assignee: MarcTec LLC
• Inventors: Bonutti, Peter M.
• Primary Examiner(s): Douglas; Steven O.
• Application Number:
  US10/990,871
• Publication Number:
  US 20050103334A1
• Time in Patent Office: 1,161 Days
• Field of Search: 128/200.25, 128/205.23, 128/207.14, 128/207.15, 128/207.29, 600/109, 600/409, 600/410, 600/424, 604/93.01
• US Class Current: 128/200.24
• CPC Class Codes: A61B 1/00082 Balloons
• CPC Class Codes: A61B 1/00124 electrical, e.g. electrical plug-and-socket connection
• CPC Class Codes: A61B 1/005 Flexible endoscopes
• CPC Class Codes: A61B 1/015 Control of fluid supply or evacuation
• CPC Class Codes: A61B 1/0676 at distal tip of an endoscope
• CPC Class Codes: A61B 1/0684 using light emitting diodes [LED]
• CPC Class Codes: A61B 1/07 using light-conductive means, e.g. optical fibres
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 8/0841 for locating instruments
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4254 using sensors mounted on the probe
• CPC Class Codes: A61B 8/4263 using sensors not mounted on the probe, e.g. mounted on an external reference frame
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/461 Displaying means of special interest
• CPC Class Codes: A61M 16/0411 with means for differentiating between oesophageal and tracheal intubation
• CPC Class Codes: A61M 16/0434 Cuffs
• CPC Class Codes: A61M 16/0488 Mouthpieces; Means for guiding, securing or introducing the tubes guiding or introducing with laryngoscopes A61B1/267; holding devices on the body A61M25/02
• CPC Class Codes: A61M 16/0495 with tongue depressors
• CPC Class Codes: A61M 16/0497 Tube stabilizer
• CPC Class Codes: A61M 2025/0008 having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
• CPC Class Codes: A61M 2025/022 : specifically adapted for the mouth
• CPC Class Codes: A61M 2025/09008 : having a balloon
• CPC Class Codes: A61M 2025/091 : having a lumen for drug delivery or suction
• CPC Class Codes: A61M 2205/0272 : Electro-active or magneto-active materials
• CPC Class Codes: A61M 2205/587 : Lighting arrangements
• CPC Class Codes: A61M 25/0102 : Insertion or introduction using an inner stiffening member, e.g. stylet or push-rod
• CPC Class Codes: A61M 25/0108 : using radio-opaque or ultrasound markers
• CPC Class Codes: A61M 25/09 : Guide wires

Abstract

A tracheal tube positioning apparatus is located relative to a patient'"'"'s trachea by engaging the patient'"'"'s Adam'"'"'s apple. Indicia on relatively movable sections of the positioning apparatus provides an indication of the distance between the patient'"'"'s mouth and the patient'"'"'s larynx. A flexible guide rod is moved through a distance corresponding to the distance between the patient'"'"'s mouth and larynx, as determined by the positioning apparatus. A magnet is utilized to attract a leading end portion of the guide rod. A plurality of emitters may be disposed in an array around the patient'"'"'s Adam'"'"'s apple. Outputs from the emitters are detected by a detector connected with the guide rod and by a detector connected with the tracheal tube. Alternatively, a plurality of detectors may be disposed in an array around the patient'"'"'s Adam'"'"'s apple to detect the output from an emitter connected with the guide rod and by an emitter connected with the tracheal tube. Expandable elements may be connected with the guide rod and/or tracheal tube to steer movement along an insertion path.

Claims

1. A method for administering a medicant at a treatment site in a body of a patient, the method comprising:

providing a medical device including a leading end portion insertable into the body of the patient;

releasably holding substantially all of the medicant to be released in a holder,

said holder disposed proximate to the leading end portion of the medical device;

inserting the leading end portion, including said holder holding the medicant, into the body of the patient;

moving the leading end portion of the medical device along an insertion path in the body of the patient, including attracting the leading end portion of the medical device with a magnetic field extending to a location outside of the patient'"'"'s body; and

releasing the medicant at the treatment site.

2. The method of claim 1 further comprising:

applying a force against a trailing end portion of the medical device to move the medical device along the insertion path; and

steering the leading end portion of the medical device along the insertion path under the influence of the magnetic field.

3. The method of claim 1 further comprising moving the magnetic field relative to the body of the patient.

4. The method of claim 1 further comprising adjusting the strength of the magnetic field.

5. The method of claim 1 wherein the magnetic field is generated by a permanent magnet or an electromagnet located proximate to the leading end portion or located external to the body.

6. A medicant delivery system for administering a medicant at a treatment site in a body of a patient, the system comprising:

an elongated flexible member including a leading end portion configured and dimensioned for insertion into a passage in the body of the patient;

a medicant holder disposed proximate to the leading end portion and operative to hold a dose of the medicant to be delivered;

a first magnetically attractive member for directing the leading end portion of the medical device through the passage to the treatment site; and

means for releasing the medicant held in said holder from said holder when the leading end portion is at the treatment site.

7. The system of claim 6 wherein the magnet has sufficient strength to alter the direction of the leading end portion of the medical device.

8. The system of claim 6 further including an actuator for operating the holder from a closed position in which the medicant is held to an open position in which at least a quantity the medicant is released from the leading end portion.

24. The system of claim 6, wherein said first magnetically attractive member is associated with said leading end portion, and further comprising:

a second magnetically attractive element;

means for connecting said flexible elongated medical device to said second magnetically attractive element;

whereby said means for connecting is operable to position said second magnetically attractive element external to the body proximate to said first magnetically attractive member internal to the body.

25. The system of claim 6, wherein said means for releasing is a Bowden cable or an actuator extending through the flexible elongated member to the medicant holder.

9. A method for administering a medicant at a treatment site in a body of a patient, said method comprising:

locating a positioning apparatus relative to an external portion of the patient'"'"'s body by engaging the patient'"'"'s body with the positioning apparatus;

releasably holding subtantially all of a medicant to be released in a holder disposed proximate to a leading end portion of an elongated member;

determining a position to which the leading end portion of the elongated member is to be moved relative to the positioning apparatus;

moving the elongated member into the patient'"'"'s body while the positioning apparatus is in engagement with the patient'"'"'s body;

interrupting movement of the elongated member into the patient'"'"'s body when the leading end portion of the elongated member, together with the holder and the held medicant, has moved to the previously determined position relative to the positioning apparatus; and

releasing the medicant from the leading end portion of the elongated member while the leading end portion is in the previously determined position relative to the patient'"'"'s body.

10. The method of claim 9 wherein the step of moving an elongated member into the patient'"'"'s body includes moving at least a portion of the elongated member through a portion of the positioning apparatus which is aligned with an opening in the patient'"'"'s body.

11. The method of claim 9 wherein said step of locating the positioning apparatus relative to a portion of the patient'"'"'s body includes varying the spatial relationship between first and second portions of the positioning apparatus, said step of determining a position to which the leading end portion of the elongated member is to be moved relative to the patient'"'"'s body includes determining the position as a function of the spatial relationship between the first and second portions of the positioning apparatus after the positioning apparatus has been located relative to the patients body and when the positioning apparatus is disposed in engagement with the patient'"'"'s body.

12. The method of claim 9 further including the step of disengaging the positioning apparatus from the elongated member prior to performance of said step of releasing the medicant, said step of disengaging the positioning apparatus from the elongated member is performed with a portion of the elongated member in the patient'"'"'s body.

13. The method of claim 9 wherein said step of engaging a portion of the patients body with the positioning apparatus includes engaging spaced apart locations on the patient'"'"'s body with the positioning apparatus.

14. The method of claim 9 wherein said step of moving the elongated member into the patient'"'"'s body comprises magnetically attracting the leading end portion of the elongated member using a magnetic field extending from said leading end portion to a location outside of the patient'"'"'s body.

15. The method of claim 9 wherein said step of moving the elongated member into the patient'"'"'s body includes detecting when the leading end portion of the elongated member is in a position other than a desired position and applying force against the leading end portion of the elongated member to move the leading end portion of the elongated member toward the desired position.

16. The method of claim 9 further including the step of transmitting an image from the leading end portion of the elongated member to a location outside of the patient to facilitate visualization of tissue disposed in the patient'"'"'s body adjacent to the leading end portion of the elongated member.

17. The method of claim 9 further including the steps of providing a sensor assembly having an emitter portion which provides an output and a detector portion which responds to the output from the emitter portion, moving one of the emitter and detector portions of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member as the elongated member moves into the patient'"'"'s body, positioning the other of the emitter and detector portions of the sensor assembly adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus, and determining when the leading end portion of the elongated member is in a desired position relative to the patient'"'"'s body as a function of a response from the detector portion of the sensor assembly during movement of the elongated member into the patient'"'"'s body.

18. The method of claim 17 wherein said step of moving one of the emitter and detector portions of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member includes moving the emitter portion of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member, and said step of positioning the other of the emitter and detector portions of the sensor assembly adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus includes positioning the detector portion of the sensor assembly adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus.

19. The method of claim 18 wherein said step of moving the emitter portion of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member includes moving an item selected from the group consisting of a magnet, an electromagnet, and a magnetically attractable material, into the patient'"'"'s body with the leading end portion of the elongated member, and said step of positioning the detector portion of the sensor assembly adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus includes positioning a device which responds to a magnetic field adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus.

20. The method of claim 17 wherein said step of moving one of the emitter and detector portions of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member includes moving the detector portion of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member, and said step of positioning the other of the emitter and detector portions of the sensor assembly adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus includes positioning the emitter portion of the sensor assembly adjacent to the portion of the patient'"'"'s body engaged by the positioning apparatus.

21. The method of claim 20 wherein said step of moving the detector portion of the sensor assembly into the patient'"'"'s body with the leading end portion of the elongated member includes moving a first device which responds to magnetic fields into the patient'"'"'s body with the leading end portion of the elongated member, and said step of positioning the emitter portion of the sensor assembly adjacent to the portion of the patient'"'"'s body includes positioning a second device which responds to magnetic fields adjacent to the portion of the patient'"'"'s body.

22. The method of claim 9 wherein said step of moving an elongated member into the patient'"'"'s body includes moving a plurality of expandable elements into the patient'"'"'s body with the elongated member and expanding at least one of the plurality of expandable elements as the leading end portion of the elongated member is moved relative to the patient'"'"'s body.

23. The method of claim 9 wherein said step of moving the elongated member into the patient'"'"'s body includes steering the leading end portion of the elongated member by expanding an expandable element connected with the leading end portion of the elongated member.

26. The method of claim 9, further comprising the steps of:

associating an indicator with said positioning apparatus external to the body;

wherein said indicator is operative to maintain a position proximate to said leading end portion as said leading end portion is moved within the body.