Pressure sensing in implantable medical devices
First Claim
1. An implantable medical device for delivering a liquid therapeutic substance to a delivery site in a patient comprising:
- a reservoir holding a supply of said fluid therapeutic substance;
a catheter having a proximal end, a delivery region and a lumen extending from said proximal end to said delivery region, said proximal end of said catheter being operatively coupled to said reservoir, said delivery region of said catheter being adapted to be placed proximate said delivery site in said patient, said therapeutic substance adapted to be delivered through said lumen to said patient;
a sensing device operatively coupled with said lumen of said catheter being capable of detecting a pressure of said therapeutic substance in said lumen;
a controller operatively coupled to said sensing device, said controller being capable of taking an action is response to said pressure in said lumen;
wherein said therapeutic substance comprises a fluid;
wherein said therapeutic substance comprises a liquid;
wherein said sensing device is further capable of detecting a reference pressure outside of said lumen and wherein said controller is capable of taking action in response to relative pressures between said pressure in said lumen and said reference pressure outside of said lumen;
wherein said location outside of said lumen is in proximity to said delivery region of said catheter; and
wherein said lumen is a first lumen and wherein said catheter has a second lumen and wherein said location outside of said first lumen is in said second lumen.
1 Assignment
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Accused Products
Abstract
An implantable medical device for delivering a therapeutic substance to a delivery site in a patient. A reservoir holds a supply of the fluid therapeutic substance. A catheter has a proximal end, a delivery region and a lumen extending from the proximal end to the delivery region. The proximal end of the catheter is operatively coupled to the reservoir. The delivery region of the catheter is adapted to be placed proximate the delivery site in the patient. The therapeutic substance is adapted to be delivered through the lumen to the patient. A sensing device is operatively coupled with the lumen of the catheter being capable of detecting a pressure of the therapeutic substance in the lumen. A controller is operatively coupled to the sensing device, the controller being capable of taking an action in response to the pressure in the lumen.
79 Citations
41 Claims
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1. An implantable medical device for delivering a liquid therapeutic substance to a delivery site in a patient comprising:
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a reservoir holding a supply of said fluid therapeutic substance; a catheter having a proximal end, a delivery region and a lumen extending from said proximal end to said delivery region, said proximal end of said catheter being operatively coupled to said reservoir, said delivery region of said catheter being adapted to be placed proximate said delivery site in said patient, said therapeutic substance adapted to be delivered through said lumen to said patient; a sensing device operatively coupled with said lumen of said catheter being capable of detecting a pressure of said therapeutic substance in said lumen; a controller operatively coupled to said sensing device, said controller being capable of taking an action is response to said pressure in said lumen; wherein said therapeutic substance comprises a fluid; wherein said therapeutic substance comprises a liquid; wherein said sensing device is further capable of detecting a reference pressure outside of said lumen and wherein said controller is capable of taking action in response to relative pressures between said pressure in said lumen and said reference pressure outside of said lumen; wherein said location outside of said lumen is in proximity to said delivery region of said catheter; and wherein said lumen is a first lumen and wherein said catheter has a second lumen and wherein said location outside of said first lumen is in said second lumen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A drug delivery system for delivering a liquid therapeutic substance to a delivery site in a patient comprising:
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an implantable medical device, comprising; a reservoir holding a supply of said fluid therapeutic substance; and a pump fluidly coupled to said reservoir, said pump being capable of fluidly driving said therapeutic substance to said delivery site under pressure; a catheter having a proximal end, a delivery region and a lumen extending from said proximal end to said delivery region, said proximal end of said catheter being operatively coupled to said reservoir, said delivery region of said catheter being adapted to be placed proximate said delivery site in said patient, said therapeutic substance adapted to be delivered through said lumen to said patient; a sensing device operatively coupled with said lumen of said catheter being capable of detecting a pressure of said therapeutic substance in said lumen; a controller operatively coupled to said sensing device, said controller being capable of taking an action in response to said pressure in said lumen; wherein said sensing device is further capable of detecting a reference pressure outside of said lumen and wherein said controller is capable of taking action in response to relative pressures between said pressure in said lumen and said reference pressure outside of said lumen; wherein said location outside of said lumen is in proximity to said delivery region of said catheter; and
wherein said lumen is a first lumen and wherein said catheter has a second lumen and wherein said location outside of said first lumen is in said second lumen. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
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Specification