Cell delivery system comprising a fibrous matrix and cells
First Claim
1. A cell delivery system comprising a biodegradable and/or bioabsorbable fibrous matrix containing at least about 20 weight percent of fibers having fiber diameters in the range of about 10 up to about 1000 nanometers of a biodegradable and/or bioabsorbable fiberizable material, and viable cells physically associated with said matrix as a carrier whereby said cells are contained and released at a controlled rate.
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Abstract
Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.
80 Citations
15 Claims
- 1. A cell delivery system comprising a biodegradable and/or bioabsorbable fibrous matrix containing at least about 20 weight percent of fibers having fiber diameters in the range of about 10 up to about 1000 nanometers of a biodegradable and/or bioabsorbable fiberizable material, and viable cells physically associated with said matrix as a carrier whereby said cells are contained and released at a controlled rate.
Specification