System and method for neurological stimulation of peripheral nerves to treat low back pain

• US 7,324,852 B2
• Filed: 02/25/2005
• Issued: 01/29/2008
• Est. Priority Date: 02/25/2004
• Status: Active Grant

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories), Thomas Jefferson University (Main Line Health System)
• Original Assignee: Thomas Jefferson University (Main Line Health System)
• Inventors: Cameron, Tracy L., Chavez, Christopher G., Barolat, Giancarlo
• Primary Examiner(s): Layno; Carl
• Assistant Examiner(s): Gedeon; Brian T.
• Application Number:
  US11/066,669
• Publication Number:
  US 20050240243A1
• Time in Patent Office: 1,068 Days
• Field of Search: 607 46- 48
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36071 Pain

Abstract

According to one embodiment, a system for neurological stimulation of peripheral nerve fibers to treat low back pain is provided. The system includes stimulation electrodes adapted to be implanted in tissue proximate a network of peripheral nerve fibers located in and innervating a painful region of the low back area and to deliver electrical stimulation pulses to the network of peripheral nerve fibers located in and innervating the painful region of the low back area. The system also includes a stimulation source adapted for implantation into the person'"'"'s body and operable to generate electrical stimulation pulses for transmission to the electrodes for delivery to the network of peripheral nerve fibers located in and innervating the painful region of the low back area to relieve pain in the painful region of the low back area.

Claims

1. A method for stimulating localized sensory nerves to treat low back pain, comprising:

identifying a region of low back pain in a patient;

identifying a sub-region of greatest hyperalgesia within the region;

implanting one or more stimulation leads with a plurality of electrodes being disposed in the sub-region of greatest hyperalgesia and substantially aligned along a greatest axis of the region of low back pain, the implanting positioning the plurality of electrodes in the epidermis, dermis, or subcutaneous tissue superior to fascia containing a network of localized sensory nerve fibers located in and influencing the painful region of the low back area without regard to a specific or identifiable nerve or nerve branch;

using an electrical stimulation source implanted in a person'"'"'s body, generating electrical stimulation pulses for transmission to the plurality of electrodes; and

in response to the electrical stimulation pulses transmitted from the stimulation source implanted in the person'"'"'s body, treating the patient'"'"'s low back pain by using the plurality of electrodes to stimulate the network of localized sensory nerve fibers.

2. The method of claim 1, wherein the implanting positions an electrode of the plurality of electrodes immediately proximate to an epicenter of the sub-region of greatest hyperalgesia.

3. The method of claim 1, wherein the stimulation source generates the stimulation pulses according to one or more stimulation sets each specifying a plurality of stimulation parameters collectively specifically tailored to relieve pain in the painful region of the person'"'"'s low back area, the stimulation parameters for a stimulation set comprising a polarity for each electrode at each of one or more times within a stimulation pulse for the stimulation set.

4. The method of claim 1, wherein the stimulation source generates the stimulation pulses according to a plurality of stimulation programs each comprising one or more stimulation sets, each stimulation set specifying a plurality of stimulation parameters collectively specifically tailored to relieve pain in the painful region of the person'"'"'s low back area.

5. The method of claim 1, wherein delivery of the stimulation pulses to the network of localized sensory nerve fibers provides paresthesia with respect to the painful region of the person'"'"'s low back area.

6. A method of treating allodynia in a low back region of a patient, comprising:

identifying a region of allodynia in the low back region of the patient;

identifying a perimeter of the region of allodynia;

implanting one or more stimulation leads with a plurality of electrodes around the perimeter of the region of allodynia or bracketing the region of allodynia along the perimeter, the implanting positioning the plurality of electrodes in the epidermis, dermis, or subcutaneous tissue superior to fascia containing a network of localized sensory peripheral nerve fibers located in and influencing the region of allodynia without regard to a specific or identifiable nerve or nerve branch;

generating electrical pulses using an implantable pulse generator implanted in the patient, the implantable pulse generator being electrically coupled to the one or more stimulation leads; and

treating the allodynia by applying the generated electrical pulses from the implantable pulse generator to the plurality of electrodes to stimulate the network of localized sensory peripheral nerve fibers located in and influencing the region of allodynia.