Fluid transfer device

• US 7,326,194 B2
• Filed: 01/31/2002
• Issued: 02/05/2008
• Est. Priority Date: 03/20/1995
• Status: Expired due to Fees

• Current Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: Zinger, Freddy, Denenburg, Igor
• Primary Examiner(s): Lucchesi; Nicholas D.
• Assistant Examiner(s): Ahmed; Aamer S.
• Application Number:
  US10/062,796
• Publication Number:
  US 20020087144A1
• Time in Patent Office: 2,196 Days
• Field of Search: 604/126, 604/403, 604/405, 604/406, 604/411, 604/412, 604/413, 604/414, 604/415, 604/190, 604/537, 604/539, D24/129, D24/130, 215/247, 215/249, 215/DIG.163
• US Class Current: 604/410
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2013 having two piercing ends
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2039/1077 Adapters, e.g. couplings adapting a connector to one or several other connectors
• CPC Class Codes: A61M 39/18 Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 5/162 Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube in jet-action syringes A61M5/30; connectors for tubes having sealed ends and a needle for piercing them A61M39/14

Abstract

A fluid ducting assembly for enabling flow communication between a syringe and either one of a vessel and a dispenser for dispensing a fluid contained, a priori in the syringe or in the vessel. The fluid ducting assembly includes a base having a first member, a second member, and a third member for connection to and providing flow communication with the syringe, the vessel and the dispenser, respectively. The fluid ducting assembly further includes a flow controller within the base enabling any one of a flow path between the first member and the second member and a flow path between the first member and the third member. The flow controller has either a first operative position in which the flow path between the first member and the second member is enabled or a second operative position in which the flow path between the first member and the third member is enabled. The flow controller being readily switchable from its first operative position to its second operative position but not readily switchable from its second operative position to its first operative position.

Claims

1. A fluid transfer device having a longitudinal axis for use with a vial having a container portion, an upper, generally cylindrically shaped portion with a lower edge and an intermediate neck portion, said fluid transfer device comprising:

(a) a top wall; and

(b) a resiliently deformable circumferential skirt connected to said top wall and downwardly depending therefrom for telescopically receiving the upper portion of the vial, said skirt having;

(i) a generally cylindrical body portion;

(ii) an angularly outwardly extending marginal portion including a distal end;

(iii) an angularly inwardly extending intermediate portion disposed between said body portion and said outwardly extending marginal portion, said inwardly extending intermediate portion including at least partially circumferentially-extending opposing protuberances for releasably gripping the vial, at least a portion of the marginal portion extending substantially directly from the protuberances; and

(iv) a cannula connected to said top wall and downwardly depending therefrom for extending into the vial received in said adapter, said cannula including a puncturing tip located between said top wall and said distal end along said longitudinal axis,

wherein said skirt is formed with a plurality of circumferentially spaced apart longitudinally directed slits for defining flex members resiliently flexibly connected at said top wall between each adjacent pair of longitudinally directed slits of said plurality of circumferentially spaced apart longitudinally directed slits,

wherein said outwardly extending marginal portions of said flex members positively assist in guiding said upper portion of said vial into said adapter through outward flexure of said flex members resulting in an expanded insertion angle for said vial, at least two opposing flex members of said plurality of said flex members include said at least two opposing protuberances on said intermediate portion to engage said vial in an engaged position.

2. The fluid transfer device as defined in claim 1 further including a connector portion connected to said top wall and filter means for filtering the fluid within the vial, said filter means being carried by said connector portion.

3. The fluid transfer device as defined in claim 1 further including venting means for providing an air passageway between the interior of the vial and atmosphere.

4. The fluid transfer device as defined in claim 1, further including a connector portion connected to said top wall having a tapered bore having a cavity formed therein and further includes a filter disposed within said cavity.

5. The fluid transfer device as defined in claim 1, wherein said cannula includes first and second spaced apart lumens, said second lumen defining a venting passageway for permitting the flow of air between the interior of the vial and the exterior thereof.

6. The fluid transfer device as defined in claim 1 further including filter means carried by said top wall for filtering air flowing toward the exterior of the vial.

7. The fluid transfer device as defined in claim 6 in which said filter means comprises a filter that permits the flow of liquid therethrough, but prevents the flow of air therethrough.

8. The fluid transfer device as defined in claim 1 in which said fluid transfer device is molded in a single piece from a moldable plastic.

9. The fluid transfer device as defined in claim 1, further including a connector portion connected to said top wall, said connector portion includes a tapered bore having an upper portion having an inwardly tapering wall and a lower portion having an outwardly tapering wall.

10. The fluid transfer device as defined in claim 9 further including filter means disposed within said lower portion of said tapered bore for filtering fluid flowing through said tapered bore.

11. The fluid transfer device as defined in claim 1 in which said angularly outwardly extending marginal portion has a length at least one-third (⅓

) the length of said generally cylindrical body portion.

12. The fluid transfer device as defined in claim 1 further including a connector portion extending generally perpendicularly from said top wall opposite said cannula.

13. The fluid transfer device as defined in claim 1 wherein each of said plurality of said flex members includes one of said protuberances, each of said protuberances engaging said lower edge of said vial in said engaged position.

14. The fluid transfer device as defined in claim 1 wherein said at least two protuberances of said intermediate portion extend generally around an entire circumference of said skirt and engage said lower edge in the engaged position.

15. The fluid transfer device as defined in claim 1 wherein said puncturing tip is located on said longitudinal axis generally on a plane defined by said intermediate portion.

16. The fluid transfer device of claim 1 wherein said marginal portion extends generally tangentially from the protuberances.

17. A fluid transfer device for use with a vial having an upper, generally cylindrically-shaped portion with a lower edge and a stopper mounted therein, an intermediate neck portion and a container portion for holding a fluid, the fluid transfer device comprising:

a top wall positioned on a plane that is generally perpendicular to a longitudinal axis of the fluid transfer device;

a generally cylindrical body portion extending generally perpendicularly from the top wall, the body portion defining a receiving area;

an intermediate portion extending from the body portion, the intermediate portion including at least two inwardly extending, opposing protuberances for releasably gripping the vial in an engaged position;

a marginal portion extending outwardly from the intermediate portion at a guiding angle, the marginal portion having a generally hollow, frustaconical-shape and a distal end;

a cannula extending generally perpendicularly from the top wall coaxial with the longitudinal axis into the receiving area, the cannula having a puncturing tip that is located along the longitudinal axis between the top wall and the distal end; and

at least two circumferentially spaced, longitudinal slits extending through the body portion, the intermediate portion and the marginal portion, the at least two longitudinal slits defining at least two flex members resiliently, flexibly connected to the top wall, at least one of the flex members having an intermediate circumferential width defined between the at least two slits proximate the intermediate portion and an end circumferential width defined between the at least two slits proximate the distal end, the end width being greater than the intermediate width, the marginal portion of the at least two flex members guiding the upper portion of the vial into the receiving area such that the at least two opposing protuberances engage the vial and the cannula extends into the stopper in the engaged position.

18. The fluid transfer device of claim 17 wherein the at least two longitudinal slits are comprised of six longitudinal slits extending through the body portion, the intermediate portion and the marginal portion, the six longitudinal slits defining six flex members.

19. The fluid transfer device of claim 18 wherein each of the six flex members include the intermediate portion with at least one of the at least two protuberances.

20. The fluid transfer device of claim 18 wherein the at least two protuberances are comprised of six protuberances, each of the six flex members include one of the six protuberances.

21. The fluid transfer device of claim 18 wherein the end width is greater than the intermediate width for each of the six flex members.

22. The fluid transfer device of claim 18 wherein the end width is greater than the intermediate width for each of six flex members.

23. The fluid transfer device of claim 17 wherein the guiding angle is at least twenty-five degrees (25°

).

24. The fluid transfer device of claim 17 wherein the guiding angle is between twenty-five degrees (25°

) and forty-five degrees (45°

).

25. The fluid transfer device of claim 24 wherein the guiding angle is approximately thirty degrees (30°

).

26. The fluid transfer device of claim 17 further comprising:

a bead extending from the marginal portion, the bead having a terminal end spaced from the marginal portion, the terminal end having a generally circular cross-sectional shape.

27. The fluid transfer device of claim 26 wherein the at least two longitudinal slits extend from a first end proximate the top wall to the terminal end, the at least two longitudinal slits extending through the body portion, the intermediate portion, the marginal portion and the bead.

28. The fluid transfer device of claim 17 further comprising:

a connector portion extending generally perpendicular from the top wall along the longitudinal axis opposite the cannula, the connector portion including a tapered bore, the tapered bore being in fluid communication with the cannula.

29. The fluid transfer device of claim 28 wherein the connector portion includes a reverse taper socket therein proximate the top wall.

30. The fluid transfer device of claim 29 further comprising:

a filter secured within the reverse taper socket.

31. The fluid transfer device of claim 17 wherein the top wall, body portion, intermediate portion, marginal portion and cannula are constructed of an integrally molded polymeric material.

32. The fluid transfer device of claim 17 further comprising:

a bead having a terminal end extending from the marginal portion, the terminal end located a first distance from the top wall, the puncturing tip located a second distance from the top wall, the first distance being greater than the second distance.

33. The fluid transfer device of claim 17 wherein the guiding angle changes when the at least two flex members flex to accommodate insertion of the upper portion of the vial into the receiving area.

34. The fluid transfer device of claim 17 wherein the at least two flex members snap lock the body portion to the upper portion of the vial in the engaged position and the at least two protuberances beneath the lower edge.

35. The fluid transfer device of claim 17 wherein the at least two opposing protuberances extend generally around an entire circumference of the fluid transfer device.

36. The fluid transfer device of claim 17 wherein the cannula has a generally conically-shaped puncturing tip.

37. The fluid transfer device of claim 17 wherein the slits have a generally uniform width along an entire length of the slits.