Analysis of eating habits

• US 7,330,753 B2
• Filed: 04/16/2002
• Issued: 02/12/2008
• Est. Priority Date: 04/18/2001
• Status: Expired due to Term

• Current Assignee: Tylerton International Inc.
• Original Assignee: Metacure NV
• Inventors: Policker, Shai, Aviv, Ricardo, Biton, Ophir
• Primary Examiner(s): Layno; Carl
• Assistant Examiner(s): Malamud; Deborah
• Application Number:
  US10/475,198
• Publication Number:
  US 20040147816A1
• Time in Patent Office: 2,128 Days
• Field of Search: 607/2, 607 40- 41, 607/45, 607/58, 607/62, 600/300, 600/546, 600/547, 600/585, 600/593, 128/898, 128/903, 128/920, 128/924, 128/925
• US Class Current: 600/546
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/392 Detecting gastrointestinal contractions
• CPC Class Codes: A61B 5/4023 Evaluating sense of balance
• CPC Class Codes: A61B 5/42 Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence
• CPC Class Codes: A61B 5/4233 oesophagus
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: Y10S 128/903 Radio telemetry
• CPC Class Codes: Y10S 128/92 Computer assisted medical diagnostics

Abstract

Diet evaluation gastric apparatus (18) is provided, which detects when a patient (10) swallows, and detects the type and amount of matter ingested. The apparatus includes electrodes (74, 100) adapted to be coupled to the fundus and antrum of the patient and to measure electrical and mechanical activity therein, and a control unit (90) to analyze such electrical and mechanical activity and optionally apply electrical energy to modify the activity of tissue of the patient.

Claims

1. A method for analyzing gastric function of a stomach of a subject, comprising:

coupling a gastrointestinal sensor to a gastrointestinal site of the subject, and sensing a property of the gastrointestinal site using the gastrointestinal sensor;

coupling a set of one or more antral sensors to an antral site of an antrum of the stomach, and sensing a property of the antrum using the set of one or more antral sensors;

analyzing the property of the gastrointestinal tract and the property of the antrum; and

determining, responsive to the analysis, a characteristic of a food ingested by the subject,

wherein sensing the property of the gastrointestinal tract comprises sensing a property of a fundus of the stomach,

wherein sensing the property of the fundus comprises sensing an electrical current in the fundus, and wherein sensing the property of the antrum comprises sensing an electrical current in the antrum, and

wherein sensing the current in the fundus comprises sensing a current indicative of a measure of electrical impedance between two sites of the fundus.

2. The method according to claim 1, wherein the characteristic of the ingested food includes a caloric content of the ingested food, and wherein the method comprises determining the caloric content.

3. The method according to claim 1, wherein the characteristic of the ingested food includes a chemical content of the ingested food, and wherein the method comprises determining the chemical content.

4. The method according to claim 1, wherein the characteristic of the ingested food includes a nutritional content of the ingested food, and wherein the method comprises determining the nutritional content.

5. The method according to claim 1, and comprising receiving a control signal from a source outside of the subject.

6. The method according to claim 1, and comprising storing an ingestion schedule and generating an external cue when the analysis performed is indicative of the subject not eating in accordance with the ingestion schedule.

7. The method according to claim 1, wherein sensing the current in the antrum comprises sensing a current generated responsive to a contraction of a muscle of the antrum.

8. The method according to claim 1, wherein sensing the current in the fundus comprises sensing a current generated responsive to a contraction of a muscle of the fundus.

9. The method according to claim 1, and comprising driving a current into tissue of the subject responsive to the analysis.

10. The method according to claim 9, wherein driving the current comprises driving the current into a site of the stomach of the subject.

11. The method according to claim 9, wherein driving the current comprises driving the current into the tissue responsively to the characteristic of the ingested food.

12. The method according to claim 9, wherein driving the current comprises driving the current into the tissue responsively to a time of the subject eating.

13. The method according to claim 9, wherein driving the current comprises applying an Excitable-Tissue Control (ETC) signal to the tissue.

14. The method according to claim 13, wherein applying the ETC signal comprises increasing an aspect of contraction of the tissue.

15. The method according to claim 13, wherein applying the ETC signal comprises increasing a sensation of satiation of the subject.

16. The method according to claim 1, wherein determining the characteristic of the ingested food comprises assessing a spike energy per antral cycle of electrical activity.

17. The method according to claim 1, wherein determining the characteristic of the ingested food comprises assessing a duration of electrical activity of the antrum.

18. The method according to claim 1, wherein determining the characteristic of the ingested food comprises assessing a rate of antral electrical events.

19. The method according to claim 1, comprising identifying a reduction in a rate of antral electrical events as being indicative of an onset of antral digestion.

20. The method according to claim 1, wherein determining the characteristic of the ingested food comprises determining an extent to which the ingested food includes solid food matter.

21. The method according to claim 1, wherein determining the characteristic of the ingested food comprises determining that the ingested food includes liquid food matter.

22. A method for analyzing gastric function of a stomach of a subject, comprising:

coupling a gastrointestinal sensor to a gastrointestinal site of the subject, and sensing a property of the gastrointestinal site using the gastrointestinal sensor;

coupling a set of one or more antral sensors to an antral site of an antrum of the stomach, and sensing a property of the antrum using the set of one or more antral sensors;

analyzing the property of the gastrointestinal tract and the property of the antrum; and

determining, responsive to the analysis, a characteristic of a food ingested by the subject,

wherein sensing the property of the gastrointestinal tract comprises sensing a property of a fundus of the stomach,

wherein sensing the property of the fundus comprises sensing an electrical current in the fundus, and wherein sensing the property of the antrum comprises sensing an electrical current in the antrum, and

wherein determining the characteristic of the ingested food comprises determining the characteristic responsive to a time delay between an onset of eating and an onset of a decreased rate of electrical events in the antrum.

23. A method for analyzing gastric function of a stomach of a subject, comprising:

coupling a gastrointestinal sensor to a gastrointestinal site of the subject, and sensing a property of the gastrointestinal site using the gastrointestinal sensor;

coupling a set of one or more antral sensors to an antral site of an antrum of the stomach, and sensing a property of the antrum using the set of one or more antral sensors;

analyzing the property of the gastrointestinal tract and the property of the antrum; and

determining, responsive to the analysis, a characteristic of a food ingested by the subject,

wherein sensing the property of the gastrointestinal tract comprises sensing a property of a fundus of the stomach,

wherein sensing the property of the fundus comprises sensing an electrical current in the fundus, and wherein sensing the property of the antrum comprises sensing an electrical current in the antrum, and

wherein determining the characteristic of the ingested food comprises determining the characteristic responsive to a time delay between an onset of eating and an onset of increased electrical activity in the antrum.

24. A method for analyzing gastric function of a stomach of a subject, comprising:

coupling a gastrointestinal sensor to a gastrointestinal site of the subject, and sensing a property of the gastrointestinal site using the gastrointestinal sensor;

coupling a set of one or more antral sensors to an antral site of an antrum of the stomach, and sensing a property of the antrum using the set of one or more antral sensors;

analyzing the property of the gastrointestinal tract and the property of the antrum; and

determining, responsive to the analysis, a characteristic of a food ingested by the subject,

wherein sensing the property of the gastrointestinal tract comprises sensing a property of a fundus of the stomach, and

wherein sensing the property of the fundus comprises sensing a measure of electrical impedance between two sites of the fundus, and wherein sensing the property of the antrum comprises sensing an electrical current in the antrum.