Implantable heart assist system and method of applying same
First Claim
1. A method for increasing perfusion through a renal artery, the method comprising:
- providing fluid communication between a conduit and means for pumping blood;
advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; and
operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery;
wherein advancing further comprises advancing the conduit to a location in the vasculature having a width that is meaningfully larger than the width of the conduit.
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Accused Products
Abstract
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient'"'"'s heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient'"'"'s vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient'"'"'s heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient'"'"'s vasculature.
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Citations
24 Claims
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1. A method for increasing perfusion through a renal artery, the method comprising:
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providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; and operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery; wherein advancing further comprises advancing the conduit to a location in the vasculature having a width that is meaningfully larger than the width of the conduit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An intravascular system for increasing perfusion through a renal artery, comprising:
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means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a transverse dimension that is meaningfully smaller than the transverse dimension of a location in the descending aorta where the conduit is positioned; and wherein the conduit comprises a first lumen in which at least a portion of the pumping means is housed and a second lumen adjacent and parallel to the first lumen.
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12. A method for increasing perfusion through a renal artery, the method comprising:
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providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; and operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery; wherein the conduit has a first width and advancing comprises advancing the conduit to a location within the vasculature having a second width, the first width being less than about one-half the second width.
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13. A method for increasing perfusion through a renal artery, the method comprising:
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providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery; and providing a blood flow path in a side lumen of the conduit adjacent the pumping means.
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14. An intravascular system for increasing perfusion through a renal artery, comprising:
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means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a first cross-sectional area and a location in the descending aorta where the conduit is positioned has a second cross-sectional area, the first cross-sectional area being less than about one-half the second cross-sectional area; and wherein the pumping means further comprises pump driving means configured to be advanced into the patient'"'"'s vasculature. - View Dependent Claims (15, 16, 17)
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18. An intravascular system for increasing perfusion through a renal artery, comprising:
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means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a first cross-sectional area and a location in the descending aorta where the conduit is positioned has a second cross-sectional area, the first cross-sectional area being less than about one-half the second cross-sectional area; and wherein the conduit comprises a first lumen in which at least a portion of the pumping means is housed and a second lumen for conveying blood adjacent to the first lumen. - View Dependent Claims (19)
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20. An intravascular system for increasing perfusion through a renal artery, comprising:
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means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a first cross-sectional area and a location in the descending aorta where the conduit is positioned has a second cross-sectional area, the first cross-sectional area being less than about one-half the second cross-sectional area; and wherein the conduit comprises an inlet and an outlet, the conduit configured such that when the system is applied within the vasculature the inlet can be positioned at a first location in the descending aorta and the outlet can be positioned at a second location in the descending aorta upstream of the first location.
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21. An intravascular system for increasing perfusion through a renal artery, comprising:
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means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a transverse dimension that is meaningfully smaller than the transverse dimension of a location in the descending aorta where the conduit is positioned; and wherein the conduit comprises an inlet and an outlet, the conduit configured such that when the system is applied within the vasculature the inlet can be positioned at a first location in the descending aorta and the outlet can be positioned at a second location in the descending aorta upstream of the first location. - View Dependent Claims (22, 23, 24)
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Specification