Methods for easing pain and anxiety from atrial or ventricular defibrillation

• US 7,337,776 B2
• Filed: 07/31/2003
• Issued: 03/04/2008
• Est. Priority Date: 08/20/2002
• Status: Expired due to Fees

• Current Assignee: AGA AB (Linde Plc)
• Original Assignee: AGA AB (Linde Plc)
• Inventors: Ujhelyi, Michael R., Fishman, Royce S.
• Primary Examiner(s): MITCHELL, TEENA KAY
• Application Number:
  US10/631,911
• Publication Number:
  US 20050028816A1
• Time in Patent Office: 1,678 Days
• Field of Search: 128/200.24, 128/204.18, 128/204.22, 128/204.23, 128/204.29, 128/205.18, 128/205.22, 128/203.12, 128/203.13, 128/203.14, 128/202.28, 128/202.29, 128/203.11, 128/204.24, 607 2- 10
• US Class Current: 128/200.24
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/10 Preparation of respiratory gases or vapours
• CPC Class Codes: A61M 16/104 specially adapted for anaesthetics A61M16/18 takes precedence
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 2021/0072 with application of electrical currents
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/0225 Carbon oxides, e.g. Carbon dioxide
• CPC Class Codes: A61M 2202/0233 Carbon monoxide
• CPC Class Codes: A61M 2202/025 Helium
• CPC Class Codes: A61M 2202/0291 Xenon
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/6054 Magnetic identification systems
• CPC Class Codes: A61M 2205/6081 Colour codes
• CPC Class Codes: A61M 2205/8225 using incorporated gas cartridges for the driving gas
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance

Abstract

Methods for easing a patient'"'"'s pain and anxiety from atrial or ventricular defibrillation are disclosed. The methods include causing the patient to inhale a medical gas prior to activation of a atrial defibrillation device or subsequent to activation of a ventricular defibrillation device. In the former case, the inhalation produces analgesia, anxiolysis or anterograde amnesia prior to, during and after the atrial defibrillation. In the latter case, the inhalation produces analgesia, anxiolysis or anterograde amnesia.

Claims

1. A method of easing a patient'"'"'s pain and anxiety from atrial defibrillation comprising inhaling an effective amount of a medical gas comprising a gas selected from the group consisting of N₂O/O₂/He, N₂O/O₂ and N₂O/O₂/N₂ from a medical gas administration device for a period of up to six minutes, activating an atrial defibrillation device in connection with said patient being under the influence of said medical gas, and remotely communicating information relating to said activating of said atrial defibrillation device, whereby a remotely located third party can consider said information and assist said patient in inhaling said effective amount of said medical gas or in actuating said atrial defibrillation device or remotely actuating said atrial defibrillation device or remotely releasing said medical gas administration device for use, and said inhalation of said medical gas produces in said patient at least one effect selected from the group consisting of analgesia, anxiolysis, and anterograde amnesia immediately prior to, during and immediately after said activating of said atrial defibrillation device.

2. The method of claim 1 wherein said medical gas comprising N₂O/O₂ comprises from about 35% to 70% of said N₂O.

3. The method of claim 1 wherein said medical gas comprising N₂O/O₂ comprises from about 55% to 65% of said N₂O and from about 35% to 45% of said O₂.

4. The method of claim 1 wherein said atrial defibrillation device comprises an atrial fibrillation implantable cardioverter defibrillator, and wherein said medical gas is administered immediately prior to said patient'"'"'s activating of said atrial fibrillation implantable cardioverter defibrillator.

5. The method of claim 1 wherein said medical gas is administered within a period of less than about 4 minutes prior to said activating of said atrial defibrillation device.

6. The method of claim 5 wherein said medical gas is administered within a period of less than about 2 to 3 minutes prior to said activation of said atrial defibrillation device.

7. The method of claim 6 wherein said medical gas comprises N₂O/O₂ and wherein said N₂O is present in an amount between 55% and 70% thereof.

8. The method of claim 1 wherein said atrial defibrillation device comprises a temporary catheter.

9. A method of easing a patient'"'"'s pain and anxiety from ventricular defibrillation comprising activating a ventricular defibrillation device and subsequently inhaling an effective amount of a medical gas selected from the group consisting of N₂O/O₂, N₂O/O₂/He, N₂O/O₂/N₂, whereby said inhalation of said medical gas produces in said patient at least one effect selected from the group consisting of analgesia, anxiolysis, and anterograde amnesia.

10. The method of claim 9 wherein said medical gas comprises a gas selected from the group consisting of N₂O/O₂/He, N₂O/O₂, N₂O/O₂/N₂, Xe/O₂, Xe/O₂/N₂, and Xe/O₂/He.

11. The method of claim 10 wherein said medical gas comprising N₂O/O₂ comprises from about 35% to 70% of said N₂O.

12. The method of claim 11 wherein said medical gas comprising N₂O/O₂ comprises from about 55% to 65% of N₂O and from about 35% to 45% of said O₂.

13. The method of claim 9 wherein said ventricular defibrillation device is selected from the group consisting of a ventricular fibrillation implantable cardioverter defibrillator and a automatic external defibrillator, and wherein said medical gas is administered subsequent to said activating of said ventricular defibrillation device.

14. The method of claim 13 wherein said ventricular fibrillation implantable cardioverter is activated automatically and said subsequent inhaling of said medical gas is self-administered by said patient.

15. The method of claim 13 wherein said automatic external defibrillator is activated by a third party.

16. The method of claim 9 wherein said medical gas is administered for a period of up to about 4 minutes and subsequent to said activating of said ventricular defibrillation device.

17. The method of claim 16 wherein said medical gas is administered within a period of about 2 to 3 minutes subsequent to said activating of said ventricular defibrillation device.

18. The method of claim 9 wherein said medical gas comprises N₂O/O₂ and wherein said N₂O is present in an amount of between 55% and 70% thereof.

23. The method of claim 9 including remotely communicating information relating to said activating of said ventricular defibrillation device whereby a remotely located third party can consider said information and assist said patient in inhaling said effective amount of said medical gas or activating said ventricular defibrillation device or administering said inhaling of said effective amount of said medical gas by said patient.

19. A method of easing a patient'"'"'s pain and anxiety from atrial defibrillation comprising inhaling an effective amount of a medical gas selected from the group consisting of N₂O/O₂, N₂O/O₂/He, and N₂O/O₂/N₂ and activating a defibrillation device selected from the group consisting of implantable cardiac management devices, and external cardiac rhythm management devices while said patient is under the influence of said medical gas, said medical gas being administered for a period of up to four minutes prior to said activating of said defibrillation device, whereby said inhalation of said medical gas produces in said patient at least one effect selected from the group consisting of analgesia, anxiolysis, and anterograde amnesia immediately prior to, during, and immediately after said activating of said atrial defibrillation device.

20. The method of claim 19 wherein said N₂O/O₂ comprises from about 35% to 70% of said N₂O.

21. The method of claim 20 wherein said medical gas comprising N₂O/O₂ comprises from about 55% to 65% of said N₂O and from about 35% to 45% of said O₂.

22. The method of claim 21 wherein said medical gas is administered within a period of less than about 2 to 3 minutes prior to said activation of said atrial defibrillation device.

24. A method of easing a patient'"'"'s pain and anxiety from defibrillation comprising providing said patient with a medical gas administration device containing a predetermined dose of said medical gas whereby said patient can inhale an effective finite amount of said medical gas over a short period of time, and activating a defibrillation device selected from the group consisting of implantable cardiac management devices and external cardiac rhythm management devices prior to or following inhalation of said effective finite amount of said medical gas by said patient, said inhalation of said medical gas producing in said patient at least one effect selected from the group consisting of analgesia, anxiolysis, and anterograde amnesia immediately prior to, during and immediately after said activating of said atrial defibrillation device.

25. The method of claim 24 wherein said predetermined dose of said medical gas provides an amount of said medical gas for inhalation for a period of up to six minutes.

26. The method of claim 24 wherein said predetermined dose of said medical gas provides an amount of said medical gas for inhalation for a period of up to four minutes.

27. The method of claim 24 wherein said medical gas comprises a gas selected from the group consisting of N₂O/O₂/He, N₂O/O₂, N₂O/O₂/N₂, Xe/O₂, Xe/O₂/N₂, and Xe/O₂/He.

28. The method of claim 24 wherein said medical gas is administered within a period of less than about 4 minutes prior to said activating of said atrial defibrillation device.

29. The method of claim 24 wherein said medical gas is administered within a period of less than about 2 to 3 minutes prior to said activation of said atrial defibrillation device.

30. The method of claim 29 wherein said medical gas comprises N₂O/O₂ and wherein said N₂O is present in an amount between 55% and 70% thereof.