Sample preparation integrated chip
First Claim
1. An apparatus comprising:
- a substrate having a least one assay station;
an arrangement of at least one first multipurpose channel and at least one second multipurpose channel wherein said at least one assay station being situated in a position intermediate between said first and second multipurpose channels and in fluid communication therewith, wherein said first multipurpose channel has at least one surface characteristic conducive to conduction of a sample fluid therethrough and into said at least one assay station;
at least one sample fluid inlet in communication with said at least first multipurpose channel;
at least one isolation-medium inlet in communication with said at least first and second multipurpose channels to enable isolation medium to flow along said at least first and second multipurpose channels to isolate said at least one assay station after conduction of the sample fluid into said at least one assay station, said at least one second multipurpose channel having at least one surface characteristic non-conducive to conduction of said sample fluid; and
at least one isolation medium outlet in communication with each of said first and second multipurpose channels, thereby allowing the isolation medium to flow in to said first and second multipurpose channels by purging the sample fluid in said first multipurpose channel and air in said second multipurpose channel through respective said outlets.
5 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to an apparatus comprising a substrate having at least one assay station. The at least one assay station has at least a first assay station channel and at least a second assay station channel and the first and second assay station channels each separately being in communication with the at least one assay station. The apparatus has an arrangement of at least first and second multipurpose channels in communication with the first and second assay station channels, respectively. The first multipurpose channel and first assay station channel have internal surface characteristics conducive to conduction of a sample solution therethrough. There is at least one sample fluid inlet in communication with the at least first multipurpose channel, and at least one isolation-medium inlet in communication with the at least first and second multipurpose channels. The at least one second multipurpose channel has an internal surface portion non-conducive to conduction of said sample solution.
238 Citations
62 Claims
-
1. An apparatus comprising:
-
a substrate having a least one assay station; an arrangement of at least one first multipurpose channel and at least one second multipurpose channel wherein said at least one assay station being situated in a position intermediate between said first and second multipurpose channels and in fluid communication therewith, wherein said first multipurpose channel has at least one surface characteristic conducive to conduction of a sample fluid therethrough and into said at least one assay station; at least one sample fluid inlet in communication with said at least first multipurpose channel; at least one isolation-medium inlet in communication with said at least first and second multipurpose channels to enable isolation medium to flow along said at least first and second multipurpose channels to isolate said at least one assay station after conduction of the sample fluid into said at least one assay station, said at least one second multipurpose channel having at least one surface characteristic non-conducive to conduction of said sample fluid; and at least one isolation medium outlet in communication with each of said first and second multipurpose channels, thereby allowing the isolation medium to flow in to said first and second multipurpose channels by purging the sample fluid in said first multipurpose channel and air in said second multipurpose channel through respective said outlets. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62)
-
Specification