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Abuse-resistant hydrocodone compounds

  • US 7,338,939 B2
  • Filed: 09/30/2004
  • Issued: 03/04/2008
  • Est. Priority Date: 09/30/2003
  • Status: Active Grant
First Claim
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1. A compound comprising hydrocodone, or a pharmaceutically acceptable salt thereof, covalently attached at the 6'"'"' position to the C-terminus of a peptide wherein said peptide is Glu-Glu-Phe-Phe-Ile [SEQ ID NO:

  • 5], Glu-Glu-Phe-Phe-Phe [SEQ ID NO;

    3], Asp-Asp-Ile, Tyr-Tyr-Phe-Phe-Ile [SEQ ID NO;

    4], or Tyr-Tyr-Ile.

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