Methods and apparatus for a remote, noninvasive technique to detect core body temperature in a subject via thermal imaging

• US 7,340,293 B2
• Filed: 05/25/2004
• Issued: 03/04/2008
• Est. Priority Date: 05/27/2003
• Status: Active Grant

• Current Assignee: Cardiowave Incorporated
• Original Assignee: Cardiowave Incorporated
• Inventors: McQuilkin, Gary L.
• Primary Examiner(s): Smith; Ruth S.
• Application Number:
  US10/854,574
• Publication Number:
  US 20040254472A1
• Time in Patent Office: 1,379 Days
• Field of Search: 600/474, 600/549, 374/121, 374/126, 374/128, 374/129, 374/133
• US Class Current: 600/474
• CPC Class Codes: A61B 5/015 By temperature mapping of body part
• CPC Class Codes: G01J 2005/0077 Imaging
• CPC Class Codes: G01J 5/0025 Living bodies ear thermometers G01J5/0011; detecting, measuring or recording for diagnostic purposes A61B5/00
• CPC Class Codes: G01J 5/53 Reference sources, e.g. standard lamps; Black bodies

Abstract

An approach to noninvasively, remotely and accurately detect core body temperature in a warm-blooded subject, human or animal, via thermal imaging. Preferred features such as the use of in-frame temperature references, specific anatomical target regions and a physiological heat transfer model help the present invention to overcome pitfalls inherent with existing thermal imaging techniques applied to physiological screening applications. This invention provides the ability to noninvasively, remotely and rapidly screen for diseases or conditions that are characterized by changes in core body temperature. One human application of this invention is the remote screening for severe acute respiratory syndrome (SARS), since fever is a common, early symptom. Other diseases and conditions that affect the core body temperature of humans or animals may also be noninvasively and remotely detected with this invention.

Claims

1. A thermal imaging system that provides core body temperature information of a distant subject, comprising

a first, in-frame temperature reference having a known temperature;

a thermal imaging device that remotely and noninvasively acquires thermal image data for a field of view that includes at least a portion of a surface of the distant subject and the first, in-frame temperature reference; and

a processor configured to use thermal image data for the first, in-frame reference and the surface portion to derive a calibrated surface temperature of said surface portion; and

said processor further configured to derive a core body temperature for the subject using the calibrated surface temperature and the ambient temperature in a manner that accounts for a heat transfer impact of the ambient temperature upon the calibrated surface temperature.

2. The thermal imaging system of claim 1, wherein said processor is further configured to identify a portion of the thermal image data that corresponds to said surface of the subject.

3. The thermal imaging system of claim 2, wherein the surface is an eye region of the subject.

4. The thermal imaging system of claim 2, wherein the surface is a forehead region of the subject.

5. The thermal imaging system of claim 1, wherein the thermal imaging system further comprises an additional in-frame temperature reference that has a known temperature and that is positioned in the field of view of the device when the thermal image of the subject is acquired;

and wherein said processor is further configured to use the thermal image data of the additional in-frame reference in order to derive said calibrated surface and a calibrated ambient temperature.

6. The thermal imaging system of claim 5, wherein said processor is further configured to linearly calibrate the thermal image data using temperature data associated with the additional in-frame temperature reference.

7. The thermal imaging system of claim 5, wherein the first and the additional in-frame temperature references are maintained at two distinct temperatures.

8. The thermal imaging system of claim 5, wherein the first and the additional in-frame temperature references have different emissivity characteristics.

9. The thermal imaging system of claim 8, wherein the first and the additional in-frame references are maintained at the same temperature.

10. The thermal imaging system of claim 1, wherein said processor is further configured to derive the calibrated surface temperature using information comprising a measured temperature of the first in-frame reference and the known temperature of the reference.

11. The thermal imaging system of claim 1, wherein said processor is further configured to use an emissivity characteristic to derive the calibrated surface temperature.

12. The thermal imaging system of claim 1, further comprising an ambient temperature reference near the surface portion of the subject, and wherein the frame of view further comprises the ambient temperature reference.

13. A method of remotely and noninvasively determining a core body temperature of a distant subject, comprising:

remotely and noninvasively acquiring thermal image data for a field of view that comprises at least a portion of a surface of the subject and a first, in-frame reference having a known temperature;

acquiring an ambient temperature near said surface;

using the thermal image data for the first, in-frame reference and the surface portion to derive a calibrated surface temperature of the surface portion; and

deriving the core body temperature of the subject using the calibrated surface portion and ambient temperatures in a manner that accounts for a heat transfer impact of ambient temperature upon the calibrated surface temperature.

14. The method of claim 13, wherein said deriving step comprises using a portion of the thermal image data that corresponds to a target area of the subject to derive the core body temperature.

15. The method of claim 14, wherein the target area is a surface of an eye region of the subject.

16. The method of claim 14, wherein the target area is a forehead region of the subject.

17. The method of claim 13, further comprising an additional in-frame temperature reference in the field of view of the device when the thermal image data of the subject is acquired.

18. The method of claim 17, wherein the calibrating step comprises using a linear calibration algorithm to calibrate the thermal image data of the surface.

19. The method of claim 13, further comprising calibrating the thermal image data for the surface portion using the thermal image data and known temperature data associated with the in-frame temperature references.

20. The method of claim 13, further comprising using an emissivity characteristic of a surface to derive a calibrated temperature for said surface.

21. The method of claim 20, wherein the first in-frame temperature reference is at a temperature higher than an expected value of the surface temperature of the subject and an additional in-frame temperature reference is at a temperature lower than an expected value of the surface temperature of the subject.

22. The method of claim 13, wherein the calibrating step comprises using a linear calibration algorithm to calibrate the thermal image data of the surface.

23. The thermal imaging system of claim 13, further comprising an ambient temperature reference near the surface portion of the subject, and wherein the frame of view further comprises the ambient temperature reference.

24. A method of screening for a fever, comprising:

remotely and noninvasively acquiring thermal image data for a field of view that comprises at least a portion of a surface of a distant subject and a first, in-frame reference having a known temperature;

acquiring an ambient temperature near said surface

using the thermal image data for the first, in-frame reference and the surface portion to derive a calibrated surface temperature of the surface portion; and

deriving the core body temperature of the subject using the calibrated thermal image data surface portion and ambient temperatures in a manner that accounts for a heat transfer impact of the ambient temperature upon the calibrated surface temperature; and

using the determined core body temperature to assess whether the subject may have a fever.

25. A method of screening for a health condition, comprising

remotely and noninvasively acquiring thermal image for a field of view that comprises at least a portion of a surface of a distant subject and a first, in-frame reference having a known temperature;

acquiring an ambient temperature near said surface;

using the thermal image data for the first, in-frame reference and the surface portion to derive a calibrated surface temperature of the surface portion; and

deriving the core body temperature of the subject using the calibrated thermal image data surface portion and ambient temperatures in a manner that accounts for a heat transfer impact of the ambient temperature upon the calibrated surface temperature; and

using the determined core body temperature to assess whether the subject may have a health condition.

26. The method of claim 25, wherein the health condition is selected from at least one of

a) SARS;

b) smallpox;

c) a health condition associated with bio-terrorism;

d) heat stroke;

e) hypothermia;

f) chronic wasting disease;

g) mad cow disease;

h) scrapies;

i) West Nile Virus; and

j) an avian disease.

27. The method of claim 25, wherein the health condition is smallpox.

28. The method of claim 25, wherein the health condition is associated with bio-terrorism.

29. The method of claim 25, wherein the health condition is selected from heat-stroke and hypothermia.

30. The method of claim 25, wherein the health condition is selected from chronic wasting disease, mad cow disease, and scrapies.

31. The method of claim 25, wherein the health condition is an avian disease.

32. The method of claim 31, wherein the avian disease is West Nile Virus.