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Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders

  • US 7,341,562 B2
  • Filed: 12/15/2004
  • Issued: 03/11/2008
  • Est. Priority Date: 12/15/2004
  • Status: Active Grant
First Claim
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1. A method for responding to a change in cerebral perfusion at a target site in a human patient, comprising:

  • calculating a variable baseline value for cerebral perfusion by sequentially measuring a first set of signals indicative of cerebral perfusion level from at least one sensor implanted in the body of the patient;

    averaging the first set of cerebral perfusion measurements to obtain a variable baseline value;

    setting a threshold value of cerebral perfusion which threshold value comprises a fixed relationship between a predetermined value and the variable baseline value;

    measuring a second set of at least one cerebral perfusion measurement;

    comparing the second set to the threshold value and if the second set is not greater than the threshold value, updating the variable baseline value by the relationship between the predetermined value and the variable baseline value.

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