Please download the dossier by clicking on the dossier button x
×

Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs

  • US 7,341,840 B2
  • Filed: 09/01/2005
  • Issued: 03/11/2008
  • Est. Priority Date: 03/05/2003
  • Status: Active Grant
First Claim
Patent Images

1. A method for screening a candidate substance for anti-inflammatory activity, comprisingcontacting a cell that expresses a Reso E receptor with the candidate substance;

  • anddetecting a biological activity mediated by the Reso E receptor, wherein the Reso E receptor is the murine Reso E receptor according to SEQ. ID NO;

    2, a rat Reso E receptor according to SEQ. ID NO;

    3 or human Reso ER1 according to SEQ. ID NO;

    1, wherein the biological activity is reduced TNF-α

    cytokine induced activation of NF-kB transcription factor relative to a cell not contacted with the candidate substance.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×