Cardiac CT system and method for planning and treatment of biventricular pacing using epicardial lead

• US 7,343,196 B2
• Filed: 05/09/2003
• Issued: 03/11/2008
• Est. Priority Date: 05/09/2003
• Status: Active Grant

• Current Assignee: APN Health, LLC, General Electric Company
• Original Assignee: GE Medical Systems Global Technology Company LLC (GE Healthcare Technologies, Inc.), Jasbir S. Sra
• Inventors: Launay, Laurent, Sra, Jasbir S., Vass, Melissa L., Okerlund, Darin R., Reddy, Shankara B.
• Primary Examiner(s): Casler; Brian L.
• Assistant Examiner(s): RAMIREZ, JOHN FERNANDO
• Application Number:
  US10/249,815
• Publication Number:
  US 20040225328A1
• Time in Patent Office: 1,768 Days
• Field of Search: 600/424, 600/427, 600/374, 606/130
• US Class Current: 600/424
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/466 adapted to display 3D data
• CPC Class Codes: A61B 6/503 for diagnosis of the heart
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: A61B 6/507 for determination of haemodynamic parameters, e.g. perfusion CT
• CPC Class Codes: A61B 6/541 involving acquisition triggered by a physiological signal
• CPC Class Codes: A61B 8/543 involving acquisition triggered by a physiological signal

Abstract

A method for planning biventricular pacing lead placement for a patient includes obtaining acquisition data from a medical imaging system and generating a 3D model of the left ventricle and thoracic wall of the patient. One or more left ventricle anatomical landmarks are identified on the 3D model, and saved views of the 3D model are registered on an interventional system. One or more of the registered saved views are visualized with the interventional system, and at least one suitable region on the left ventricle wall is identified for epicardial lead placement.

Claims

1. A method for planning biventricular pacing lead placement for a patient, the method comprising:

obtaining acquisition data from a medical imaging system;

generating a 3D model of the left ventricle and thoracic wall of the patient from the acquisition data, prior to performing a biventricular pacing procedure on the patient;

identifying one or more left ventricle anatomical landmarks on said 3D model and inserting geometric markers therein corresponding to selected ones of said anatomical landmarks;

registering saved views of said 3D model on an interventional system; and

visualizing one or more of said registered saved views with said interventional system; and

identifying, prior to utilizing said interventional system, at least one suitable region on the left ventricle wall for epicardial lead placement so as to facilitate the biventricular lead placement.

2. The method of claim 1, further comprising determining, from said 3D model, any necrosed tissue of the LV myocardium, wherein the identification of any sites of such necrosed tissue is used to eliminate said sites of such necrosed tissue from epicardial lead placement.

3. The method of claim 1, wherein said obtaining acquisition data is implemented with protocols directed for imaging the LV and thoracic wall.

4. The method of claim 1, wherein said identifying at least one suitable region further includes identifying the blood vessels on the epicardium of the left ventricle and eliminating at least one of the blood vessels and the myocardium directly under the blood vessels as a suitable region.

5. The method of claim 3, further comprising utilizing post processing software to process said acquisition data so as to generate short axis images of the LV and thoracic wall.

6. The method of claim 5, wherein said 3D model and said short axis images are visualized through a display screen associated with said interventional system.

7. The method of claim 1, further comprising obtaining a movement profile of the LV posterolateral wall.

8. The method of claim 1, wherein said obtaining acquisition data is EKG gated.

9. A method for planning biventricular pacing lead placement for a patient, the method comprising:

obtaining acquisition data from a medical imaging system using a protocol directed toward the thoracic wall and left ventricle;

segmenting said acquisition data using a 3D protocol and short axis protocols so as to visualize the thoracic wall, LV walls and epicardial fat;

generating a 3D model of the left ventricle and thoracic wall of the patient from the acquisition data, prior to performing a biventricular pacing procedure on the patient;

identifying one or more left ventricle anatomical landmarks on said 3D model and inserting geometric markers therein corresponding to selected ones of said anatomical landmarks;

registering saved views of said 3D model on an interventional system; and

visualizing one or more of said registered saved views with said interventional system; and

identifying, prior to utilizing said interventional system, at least one suitable region on the left ventricle wall for epicardial lead placement so as to facilitate the biventricular lead placement.

10. The method of claim 9, further comprising determining, from said 3D model, any necrosed tissue of the LV myocardium, wherein the identification of any sites of such necrosed tissue is used to eliminate said sites of such necrosed tissue from epicardial lead placement.

11. The method of claim 9, wherein said obtaining acquisition data is implemented with protocols directed for imaging the LV and thoracic wall.

12. The method of claim 9, wherein said identifying at least one suitable region further includes identifying the blood vessels on the epicardium of the left ventricle and eliminating at least one of the blood vessels and the myocardium directly under the blood vessels as a suitable region.

13. The method of claim 11, further comprising utilizing post processing software to process said acquisition data so as to generate short axis images of the LV and thoracic wall.

14. The method of claim 13, wherein said 3D model and said short axis images are visualized through a display screen associated with said interventional system.

15. The method of claim 9, further comprising obtaining a movement profile of the LV posterolateral wall.

16. The method of claim 9, wherein said obtaining acquisition data is EKG gated.

17. The method of claim 9, wherein said medical imaging system is one of a computed tomography system, a magnetic resonance imaging system and an ultrasound system.

18. A method for planning biventricular pacing lead placement for a patient, the method comprising:

obtaining acquisition data from a cardiac computed tomography (CT) imaging system using a protocol directed toward the thoracic wall and left ventricle;

segmenting said acquisition data using a 3D protocol and short axis protocols so as to visualize the thoracic wall, LV walls and epicardial fat;

generating a 3D model of the left ventricle and thoracic wall of the patient from the acquisition data, prior to performing a biventricular pacing procedure on the patient;

obtaining a movement profile of the posterolateral wall relative to the external chest wall;

identifying one or more left ventricle anatomical landmarks on said 3D model and inserting geometric markers therein corresponding to selected ones of said anatomical landmarks;

registering saved views of said 3D model on a fluoroscopy system; and

visualizing one or more of said registered saved views with said fluoroscopy system; and

identifying, prior to utilizing said interventional system, at least one suitable region on the left ventricle wall for epicardial lead placement so as to facilitate the biventricular lead placement.

19. The method of claim 18, further comprising determining, from said 3D model, any necrosed tissue of the LV myocardium, wherein the identification of any sites of such necrosed tissue is used to eliminate said sites of such necrosed tissue from epicardial lead placement.

20. The method of claim 18, wherein said obtaining acquisition data is implemented with protocols optimized for imaging the LV and thoracic wall.

21. The method of claim 18, wherein said identifying at least one suitable region further includes identifying the blood vessels on the epicardium of the left ventricle and eliminating at least one of the blood vessels and the myocardium directly under the blood vessels as a suitable region.

22. The method of claim 20, further comprising utilizing post processing software to process said acquisition data so as to generate short axis images of the LV and thoracic wall.

23. The method of claim 22, wherein said 3D model and said short axis images are visualized through a display screen associated with said fluoroscopy system.

24. The method of claim 19, wherein said obtaining acquisition data is EKG gated.

25. A system for planning biventricular pacing lead placement for a patient, comprising:

a medical imaging system for generating acquisition data;

an image generation subsystem for receiving said acquisition data and generating one or more 3D model images of the left ventricle and thoracic wall of the patient from the acquisition data, prior to performance of a biventricular pacing procedure on the patient;

an operator console for identifying one or more left ventricle anatomical landmarks on said one or more images and inserting geometric markers therein corresponding to selected ones of said anatomical landmarks;

a workstation including post processing software for registering saved views of said 3D model on an interventional system; and

wherein said interventional system is configured for visualizing one or more of said registered saved views therewith and identifying, prior to utilizing said interventional system, at least one suitable region on the left ventricle wall for epicardial lead placement so as to facilitate the biventricular lead placement.

26. The system of claim 25, wherein said workstation is configured for determining, from said 3D model, any necrosed tissue of the LV myocardium.

27. The system of claim 25, wherein said image generation subsystem is configured with protocols directed for imaging the LV and thoracic wall.

28. The system of claim 25, wherein said identifying at least one suitable region further includes identifying the blood vessels on the epicardium of the left ventricle and eliminating at least one of the blood vessels and the myocardium directly under the blood vessels as a suitable region.

29. The system of claim 27, wherein said post processing software is further configured to process said acquisition data so as to generate short axis images of the LV and thoracic wall.

30. The system of claim 29, further comprising a display screen associated with said interventional system, said display screen for visualizing said 3D model and said short axis images.

31. The system of claim 26, wherein said image generating subsystem is EKG gated.

32. A system for planning biventricular pacing lead placement for a patient, comprising:

a cardiac computed tomography (CT) imaging system for generating acquisition data, said CT imaging system using a protocol directed toward the thoracic wall and left ventricle;

an image generation subsystem for receiving said acquisition data and generating one or more 3D model images of the left ventricle and thoracic wall of the patient from the acquisition data, prior to performance of a biventricular pacing procedure on the patient;

said image generation subsystem further configured for segmenting said acquisition data using a 3D protocol and short axis protocols so as to visualize the thoracic wall, LV walls and epicardial fat;

an operator console for identifying one or more left ventricle anatomical landmarks on said one or more images and inserting geometric markers therein corresponding to selected ones of said anatomical landmarks;

a workstation including post processing software for registering saved views of said 3D model on a fluoroscopy system; and

wherein said fluoroscopy system is configured for visualizing one or more of said registered saved views therewith and identifying, prior to utilizing said interventional system, at least one suitable region on the left ventricle wall for epicardial lead placement so as to facilitate the biventricular lead placement.

33. The system of claim 32, wherein said workstation is configured for determining, from said 3D model, any necrosed tissue of the LV myocardium.

34. The system of claim 32, wherein said post processing software is further configured to process said acquisition data so as to generate short axis images of the LV and thoracic wall.

35. The system of claim 32, wherein said identifying at least one suitable region further includes identifying the blood vessels on the epicardium of the left ventricle and eliminating at least one of the blood vessels and the myocardium directly under the blood vessels as a suitable region.

36. The system of claim 34, further comprising a display screen associated with said fluoroscopy system, said display screen for visualizing said 3D model and said short axis images.

37. The system of claim 32, wherein said image generating subsystem is EKG gated.