Nasal delivery devices
First Claim
1. An exhalation breath-actuated nasal delivery device for delivering a substance to a nasal cavity of a subject, comprising:
- a nosepiece for filling to a nostril of a subject;
a mouthpiece through which the subject in use exhales;
a nozzle for directing a substance through the nosepiece;
a mechanical delivery pump fluidly connected to the nozzle for delivering a substance to the nozzle; and
an actuation mechanism for actuating the mechanical delivery pump in response to oral exhalation through the mouthpiece.
6 Assignments
0 Petitions
Accused Products
Abstract
An exhalation breath-actuated nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece (40) for fitting to a nostril of a subject; a mouthpiece (42) through which the subject in use exhales; and delivery unit (64), as one of a mechanical delivery pump (66) or a nebulizer (115), for delivering a substance to the nosepiece (40); and an actuation mechanism (74) for actuating the delivery unit in response to oral exhalation through the mouthpiece, and preferably when at least one or both of the pressure at or the flow rate through the nosepiece exceeds a predetermined threshold.
162 Citations
36 Claims
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1. An exhalation breath-actuated nasal delivery device for delivering a substance to a nasal cavity of a subject, comprising:
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a nosepiece for filling to a nostril of a subject; a mouthpiece through which the subject in use exhales; a nozzle for directing a substance through the nosepiece; a mechanical delivery pump fluidly connected to the nozzle for delivering a substance to the nozzle; and an actuation mechanism for actuating the mechanical delivery pump in response to oral exhalation through the mouthpiece. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of delivering a substance to a nasal cavity of a subject, comprising the steps of:
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providing a nasal delivery device to the nasal cavity of a subject, the delivery device including a nosepiece for filling to a nostril of the subject, a mouthpiece through which the subject exhales, a nozzle for directing a substance through the nosepiece, and a mechanical delivery pump fluidly connected to the nozzle for delivering a substance to the nozzle; and actuating the delivery pump in response to oral exhalation through the mouthpiece to deliver a substance through the nosepiece. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. An exhalation breath-actuated nasal delivery device for delivering a substance to a nasal cavity of a subject, comprising:
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a nosepiece for fitting to a nostril of a subject; a mouthpiece through which the subject in use exhales; a nebulizer for delivering an aerosol including a substance to the nosepiece; and an actuation unit for actuating the nebulizer when at least one or both of the pressure at or the flow rate through the nosepiece exceeds a predetermined threshold in response to oral exhalation through the mouthpiece. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29)
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30. A method of delivering a substance to a nasal cavity of a subject, comprising the steps of:
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providing a nasal delivery device comprising a nosepiece for fitting to a nostril of a subject, a mouthpiece through which the subject exhales, and a nebulizer for delivering an aerosol including a substance to the nosepiece; and actuating the nebulizer when at least one or both of the pressure at or the flow rate through the nosepiece exceeds a predetermined threshold in response to oral exhalation through the mouthpiece. - View Dependent Claims (31, 32, 33, 34, 35, 36)
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Specification