Needleless hypodermic jet injector apparatus and method
First Claim
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1. A method of hypodermically delivering a drug into a patient'"'"'s body through a patient'"'"'s skin, said method comprising:
- providing a jet injection device capable of delivering the drug into the patient'"'"'s body through the skin as a jet of liquid,forming an open electrical circuit between the patient'"'"'s body and said jet injection device,providing an electric impedance monitor connected to said electrical circuit,starting measuring the electrical impedance between the patient'"'"'s body and said jet injection device,delivering the drug into the patient'"'"'s body through the skin as a jet of liquid,closing said electrical circuit through said jet of liquid, anddetecting a change in the electrical impedance during the delivery of the drug into the patient'"'"'s body, said change indicating a success or a failure of a piercing of the skin by the jet of liquid,wherein the electric impedance is measured directly through the jet of liquid.
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Abstract
In the present invention, the impedance between patient'"'"'s body and the jet injection drug delivery device is measured through the liquid jet during the drug delivery process. The liquid jet completes the electrical circuit formed by impedance monitor, drug delivery device, and the patient'"'"'s body. When the jet pierces stratum corneum, the impedance in the circuit immediately decreases, thus an indicating the successful drug delivery. The impedance monitor then provides a signal, visible, audible, or electronic, indicating that the process of the drug delivery through skin was successful.
351 Citations
9 Claims
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1. A method of hypodermically delivering a drug into a patient'"'"'s body through a patient'"'"'s skin, said method comprising:
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providing a jet injection device capable of delivering the drug into the patient'"'"'s body through the skin as a jet of liquid, forming an open electrical circuit between the patient'"'"'s body and said jet injection device, providing an electric impedance monitor connected to said electrical circuit, starting measuring the electrical impedance between the patient'"'"'s body and said jet injection device, delivering the drug into the patient'"'"'s body through the skin as a jet of liquid, closing said electrical circuit through said jet of liquid, and detecting a change in the electrical impedance during the delivery of the drug into the patient'"'"'s body, said change indicating a success or a failure of a piercing of the skin by the jet of liquid, wherein the electric impedance is measured directly through the jet of liquid. - View Dependent Claims (2, 3, 4, 5)
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6. A method of hypodermically injecting a drug into a patient'"'"'s body and monitoring the injection success, comprising the steps of:
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providing a means for hypodermic jet injection of a drug, providing a means for monitoring an electric impedance between said means for hypodermic jet injection of the drug and the patient'"'"'s body, forming an open electrical circuit between the patient'"'"'s body and said means for hypodermic jet injection of a drug, delivering the drug utilizing said means for hypodermic jet injection of the drug into the patient'"'"'s body as a jet of liquid, measuring the electric impedance between said means for hypodermic jet injection of the drug and the patient'"'"'s body using said means for monitoring electric impedance, detecting changes in the electric impedance, said chances indicating a success or a failure of a penetration of the patient'"'"'s body by the jet of liquid, generating a signal indicating the changes in the electric impedance, wherein the electric impedance is measured directly through the jet of liquid. - View Dependent Claims (7, 8, 9)
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Specification