Fluorescent image obtaining apparatus

• US 7,349,725 B2
• Filed: 06/26/2001
• Issued: 03/25/2008
• Est. Priority Date: 06/26/2000
• Status: Expired due to Fees

• Current Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Original Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Inventors: Tsujita, Kazuhiro
• Primary Examiner(s): Casler; Brian L.
• Assistant Examiner(s): RAMIREZ, JOHN FERNANDO
• Application Number:
  US09/888,444
• Publication Number:
  US 20010056238A1
• Time in Patent Office: 2,464 Days
• Field of Search: 600473-478
• US Class Current: 600/323
• CPC Class Codes: A61B 1/043 for fluorescence imaging
• CPC Class Codes: A61B 1/045 Control thereof
• CPC Class Codes: A61B 1/0638 providing two or more wavelengths
• CPC Class Codes: A61B 1/0655 Control therefor
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/6885 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/6886 Monitoring or controlling distance between sensor and tissue
• CPC Class Codes: G01N 21/6456 Spatial resolved fluorescence measurements; Imaging
• CPC Class Codes: G01N 21/6486 Measuring fluorescence of biological material, e.g. DNA, RNA, cells G01N21/6428 takes precedence

Abstract

A fluorescent-light image obtaining apparatus for obtaining an autofluorescent-light image emitted from a target tissue irradiated by an excitation light, wherein the safety of the patient is ensured against injury from exposure to excessive excitation light when the distance between the output end of the excitation light projector and the target tissue is short. A contact detector detects that the end of the excitation light projector of the endoscope is in contact with the target tissue. Then, an excitation light output controller receives a signal indicating that the end of the excitation light projector is in contact with the target tissue. In response to this signal, the excitation light output controller stops the emission of the excitation light, or reduces the intensity of the emitted excitation light to a safe intensity for the patient even while the end of the excitation light projector and the target tissue are in contact.

Claims

1. A fluorescent-light image obtaining apparatus comprising

excitation light emitting means for projecting excitation light onto a target tissue, and

illuminating light emitting means for projecting illuminating light onto the target tissue, and

fluorescent-light image obtaining means for obtaining a fluorescent-light image formed of the fluorescent-light emitted from the target tissue upon irradiation thereof by the excitation light, and

a normal-image obtaining means for obtaining a normal-image formed of the illuminating light reflected from the target tissue upon irradiation thereof by the illuminating light, further comprising

a contact detecting means for detecting that the distal end of excitation light emitting means has come into contact with the target tissue, and

an excitation light emission controlling means for controlling, in response to the detection signal of said contact detecting means, the output of the excitation light emitted from the excitation light emitting means.

2. A fluorescent-light image obtaining apparatus as defined in claim 1, wherein

the excitation light emission control means is a current controlling means for controlling the current occurring in the excitation light source.

3. A fluorescent-light image obtaining apparatus as defined in claim 1, wherein

said excitation light emission controlling means causes the emission of the excitation light from the excitation light emitting means to stop.

4. A fluorescent-light image obtaining apparatus as defined in claim 1, wherein

said excitation light emission controlling means causes the excitation light from the excitation light emitting means to be emitted at an intensity below a predetermined value.

15. The fluorescent-light image obtaining apparatus as defined in claim 1, wherein a strength of the excitation light is controlled at the same time as the strength of the illuminating light.

17. The apparatus of claim 1, wherein the contact detecting means is attached to the distal end of the excitation light emitting means for imaging the target tissue and emits a signal to the light emission controlling means upon contact with the target tissue.

5. A fluorescent-light image obtaining apparatus comprising

excitation light emitting means for projecting excitation light onto a target tissue, and

illuminating light emitting means for projecting illuminating light onto the target tissue, and

fluorescent-light image obtaining means for obtaining a fluorescent-light image formed of the fluorescent-light emitted from the target tissue upon irradiation thereof by the excitation light, and

a normal-image obtaining means for obtaining a normal-image formed of the illuminating light reflected from the target tissue upon irradiation thereof by the illuminating light, further comprising

a distance parameter detecting means for detecting a parameter correlating the distance between the distal end of excitation light emitting means and the target tissue, and

an excitation light emission controlling means for controlling, based on the parameter detected by the distance parameter detecting means, the output of the excitation light emitted from the excitation light emitting means.

6. A fluorescent-light image obtaining apparatus as defined in claim 5, wherein

the parameter is based on the light intensity of the fluorescent-light image obtained by the fluorescent-light image obtaining means.

7. A fluorescent-light image obtaining apparatus as defined in claim 6, wherein

the parameter is based on the pixel values of the entire image or a predetermined portion of a fluorescent-light image obtained by the fluorescent-light image obtaining means.

8. A fluorescent-light image obtaining apparatus as defined in claim 5, wherein

the parameter is the light intensity of the normal-image obtained by the normal-image obtaining means.

9. A fluorescent-light image obtaining apparatus as defined in claim 8, wherein

the parameter is based on the pixel values of the entire image or a predetermined portion of a normal-image obtained by the normal-image obtaining means.

10. A fluorescent-light image obtaining apparatus as defined in claim 5, further comprising

reference-light emitting means for projecting a reference-light onto the target tissue, and

reflected-light image obtaining means for obtaining a reflected-light image reflected from the target tissue upon irradiation thereof by the reference-light, wherein

said parameter is based on the light intensity of the reflected-light image obtained by the reflected-light image obtaining means.

11. A fluorescent-light image obtaining apparatus as defined in claim 10, wherein

the parameter is based on the pixel values of the entire image or a predetermined portion of a reflected-light image obtained by the reflected-light image obtaining means.

12. A fluorescent-light image obtaining apparatus as defined in claim 5, wherein

the excitation light emission control means is a current controlling means for controlling the current occurring in the excitation light source.

13. A fluorescent-light image obtaining apparatus as defined in claim 5, wherein

said excitation light emission controlling means causes the emission of the excitation light from the excitation light emitting means to stop.

14. A fluorescent-light image obtaining apparatus as defined in claim 5, wherein

said excitation light emission controlling means causes the excitation light from the excitation light emitting means to be emitted at an intensity below a predetermined value.

16. The fluorescent-light image obtaining apparatus as defined in claim 5, wherein a strength of the excitation light is controlled at the same time as the strength of the illuminating light.