Four-dimensional volume of interest
First Claim
Patent Images
1. A method, comprising:
- interpolating between 3D models of a volume of interest (VOI) generated from 3D anatomical images captured at different points in time, wherein the VOI includes a moving 3D anatomical target;
modeling motion and deformation of the 3D anatomical target; and
planning trajectories of a radiation treatment beam before treatment to deliver radiation treatment to the moving 3D anatomical target during treatment.
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Abstract
A method and apparatus for representing a deformable volume of interest in four dimensions is described, where the four dimensions are three spatial dimensions and one temporal dimension including discrete points in time, and where the deformable volume of interest can be represented at intermediate points in time by interpolation.
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Citations
28 Claims
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1. A method, comprising:
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interpolating between 3D models of a volume of interest (VOI) generated from 3D anatomical images captured at different points in time, wherein the VOI includes a moving 3D anatomical target; modeling motion and deformation of the 3D anatomical target; and planning trajectories of a radiation treatment beam before treatment to deliver radiation treatment to the moving 3D anatomical target during treatment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. An article of manufacture, comprising a machine-accessible medium including data that, when accessed by a machine, cause the machine to perform operations comprising:
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interpolating between 3D models of a volume of interest (VOI) generated from 3D anatomical images captured at different points in time, wherein the VOI includes a moving 3D anatomical target; modeling motion and deformation of the 3D anatomical target; and planning trajectories of a radiation treatment beam before treatment to deliver radiation treatment to the moving 3D anatomical target during treatment. - View Dependent Claims (15, 16, 17, 18)
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19. An apparatus, comprising:
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a storage device to store 3D images of a volume of interest (VOI) captured at different points in time, wherein the VOI includes a moving 3D anatomical target; and a processor coupled to the storage device, the processor configured to; generate 3D models of the VOI at the different points in time; interpolate between the 3D models to model motion and deformation of the 3D anatomical target; and generate a pre-treatment radiation treatment plan comprising radiation beam trajectories to deliver radiation to the moving 3D anatomical target during treatment. - View Dependent Claims (20, 21, 22, 23, 24)
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25. A method of tracking a changing target within an anatomical region to deliver radiation to the target during motion of the anatomical region, the method, comprising:
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determining, at a time of treatment planning. a plurality of locations of the target over time using a four-dimensional volume of interest (VOI) having a fourth dimension being a time dimension; determining, at a time of treatment planning using the four-dimensional VOI, one or more radiation beam trajectories to be delivered to the target within the moving anatomical region at a time of treatment delivery, wherein determining comprises performing at least one of enabling and disabling of the one or more radiation beams depending whether the one or more radiation beams intersect the target at the plurality of locations of the target determined using the four-dimensional VOI; and generating the four-dimensional VOI, wherein generating comprises; generating a first VOI including the target at a first point in time; generating a second VOI including the target at a second point in time; registering the first VOI with the second VOI; and interpolating a third VOI including the target at a third point in time based on the registering of the first VOI with the second VOI, the third point in time being between the first and second points in time. - View Dependent Claims (26, 27)
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28. An apparatus. comprising:
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means for directly interpolating between a first contour of a first volume of interest (VOI) and a second contour of a second VOI using one or more points on the first and second contours; and means for generating an intermediate contour of an intermediate VOI based on the interpolating, wherein the means for directly interpolating comprises a four-dimensional VOI having a fourth dimension being a time dimension, and wherein the apparatus further comprises; means for determining, at a time of treatment planning, a plurality of locations of a target over time using the four-dimensional volume of interest (VOI); and means for determining, at a time of treatment planning using the four-dimensional VOI, one or more radiation beam trajectories to be delivered to the target within the moving anatomical region at a time of treatment delivery.
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Specification