Responsive therapy for psychiatric disorders

• US 7,353,065 B2
• Filed: 09/14/2004
• Issued: 04/01/2008
• Est. Priority Date: 09/14/2004
• Status: Active Grant

• Current Assignee: Neuropace Inc.
• Original Assignee: Neuropace Inc.
• Inventors: Morrell, Martha
• Primary Examiner(s): Schaetzle; Kennedy J.
• Assistant Examiner(s): Lee; Yun Haeng
• Application Number:
  US10/941,759
• Publication Number:
  US 20060058856A1
• Time in Patent Office: 1,295 Days
• Field of Search: 607/45
• US Class Current: 607/45
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

An implantable neurostimulator system for treating psychiatric disorders includes scheduled and responsive therapy capabilities including responsive stimulation applied to the cingulate gyrus of the brain. Methods for treating depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders employ an inventive system to advantageously reduce symptoms and address underlying causes of the disorders.

Claims

1. A method for treating a psychiatric disorder with an implantable apparatus in a human patient, the method comprising:

receiving a detected signal from a sensor, wherein the sensor is configured to sense information from the cingulate cortex of a patient'"'"'s brain;

identifying a detected event in the detected signal, wherein the detected signal is characteristic of the psychiatric disorder or a symptom of the psychiatric disorder;

positioning an electrode array so that a plurality of electrodes are positioned within or along the cingulate cortex so that the electrodes cover an area that extends over substantially the entire length of the cingulate cortex;

in response to the detected event, causing a therapy subsystem to apply a therapy using at least one of the electrodes in the electrode array; and

recording the information sensed from the cingulate cortex of the patient'"'"'s brain on a scheduled basis.

2. The method of claim 1, wherein the psychiatric disorder is selected from the group consisting of depression, bipolar disorder, anxiety disorder, and obsessive-compulsive disorder.

3. The method of claim 1, wherein the psychiatric disorder is selected from the group consisting of post-traumatic stress disorder, addiction, schizophrenia, autism, and a developmental disorder.

4. The method of claim 1 further comprising modifying the therapy based on the recorded information.

5. The method of claim 1, wherein the therapy is electrical stimulation.

6. The method of claim 1, wherein the sensor is implemented using at least one of the electrodes in the electrode array.

7. The method of claim 1, wherein recording the information sensed from the cingulate cortex of the patient'"'"'s brain on a scheduled basis includes recording the information sensed from the cingulate cortex of the patient'"'"'s brain substantially continuously whenever therapy is and is not being applied.

8. The method of claim 1, wherein recording the information sensed from the cingulate cortex of the patient'"'"'s brain on a scheduled basis includes recording the information sensed from the cingulate cortex of the patient'"'"'s brain substantially continuously whenever therapy is not being applied.