Diagnostic device

• US 7,354,614 B2
• Filed: 06/16/2006
• Issued: 04/08/2008
• Est. Priority Date: 06/16/2005
• Status: Expired due to Fees

• Current Assignee: British Biocell International Ltd. (Abbott Laboratories Incorporated), Porvair Filtration Group Ltd. (Porvair PLC)
• Original Assignee: British Biocell International Ltd. (Abbott Laboratories Incorporated), Porvair Filtration Group Ltd. (Porvair PLC)
• Inventors: Amey, John, Whitworth, Emma, Quinlan, Kevin Michael
• Primary Examiner(s): NGUYEN, BAO THUY L
• Application Number:
  US11/424,669
• Publication Number:
  US 20070031978A1
• Time in Patent Office: 662 Days
• Field of Search: 436/514, 436/518, 436/524, 436/538, 436/535, 436/810, 436/807, 435/7.1, 435/7.2, 435/7.8, 435/7.92, 435/7.94, 435/287.2, 435/174, 435/970, 435/971, 435/287.1, 422 58- 61
• US Class Current: 426/514
• CPC Class Codes: B01L 2300/0681 Filter
• CPC Class Codes: B01L 2300/0825 Test strips
• CPC Class Codes: B01L 3/5023 with a sample being transported to, and subsequently stored in an absorbent for analysis
• CPC Class Codes: B01L 9/52 Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
• CPC Class Codes: G01N 33/521 Single-layer analytical elements
• CPC Class Codes: G01N 33/54386 Analytical elements
• CPC Class Codes: G01N 33/54388 based on lateral flow
• CPC Class Codes: G01N 33/558 using diffusion or migration of antigen or antibody immunochromatographic test strips G01N33/54387
• CPC Class Codes: Y10S 435/97 Test strip or test slide
• CPC Class Codes: Y10S 435/971 Capture of complex after antigen-antibody reaction
• CPC Class Codes: Y10S 436/807 Apparatus included in process claim, e.g. physical support structures
• CPC Class Codes: Y10S 436/81 Tube, bottle, or dipstick

Abstract

A diagnostic device 1 for performing an immunochromatographic analysis of a sample is disclosed. The diagnostic device 1 comprises a porous substrate 10 for performing the analysis and a pre-filter 30 to remove solid components, such as solublised faeces or samples containing suspended organic material to prevent blocking of the porous substrate or coloured particles so that the test result is more clearly visible. The diagnostic device may include a container into which a sample may be provided, with the interior of the container being sealably connectable to the diagnostic section of the device. The porous section may be encapsulated within a housing.

Claims

1. A diagnostic system for performing an immunochromatographic analysis of a sample, the system comprising:

a filter operable to receive a sample to be tested,

a dosing portion that contacts the filter to receive a predetermined volume of a sample from the filter, and

a porous substrate having a visually detectable indicator arranged to bind to a ligand or other material being tested for in the sample,

wherein,

the system is configured so that the filter acts on the sample before a predetermined volume of the sample enters the dosing portion, and the dosing portion is configured to come into contact with the porous substrate to deliver the predetermined volume of the sample to the porous substrate.

2. The diagnostic device according to claim 1, wherein the filter is hydrophilic.

3. The diagnostic system according to claim 1, wherein the dosing portion is moved out of contact with the filter when the dosing portion is in contact with the porous substrate.