Optical probe for optical imaging system

• US 7,355,688 B2
• Filed: 09/08/2005
• Issued: 04/08/2008
• Est. Priority Date: 09/08/2005
• Status: Active Grant

• Current Assignee: ViOptix, Inc.
• Original Assignee: ViOptix, Inc.
• Inventors: Lash, Robert E., Mao, Jian-Min, Lin, Qiong
• Primary Examiner(s): Lauchman; Layla G.
• Application Number:
  US11/162,376
• Publication Number:
  US 20070055119A1
• Time in Patent Office: 943 Days
• Field of Search: 356/213, 356/218, 356/222, 356/446, 600/340, 600/310, 600/322, 600/342
• US Class Current: 356/222
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: G01N 21/3151 using two sources of radiation of different wavelengths G01N21/33 - G01N21/39 take precedence

Abstract

Methods and apparatus for monitoring oxygen saturation levels in tissue are disclosed. According to one aspect of the present invention, a sensor arrangement for use in an optical imaging system includes a first source structure, a second source structure, and a detector arrangement. The first source structure provides a first beam of light and the second source structure provides a second beam of light. The detector arrangement includes detector structures that have centerpoints, and receives the first and second beams of light after the first and second beams of light are reflected off of an external surface. The detector arrangement is arranged to define a first axis that passes through the centerpoint of each detector structure, and a distance from a centerpoint of the first source structure to the first axis is not equal to a distance from a centerpoint of the second source structure to the first axis.

Claims

1. A device comprising:

a first source structure, the first source structure being positioned to provide a first beam of light;

a second source structure, the second source structure being positioned to provide a second beam of light, and

a detector arrangement including a plurality of detector structures, the detector arrangement being positioned to receive the first beam of light after the first beam of light has been transmitted through a tissue, and to receive the second beam of light after the second beam of light has been transmitted through the tissue,

wherein the detector arrangement is arranged to define a first axis that passes through a centerpoint of each of the detector structures, a centerpoint of the first source structure to the first axis defines a first line segment, a centerpoint of the second source structure to the first axis defines a second line segment, which is parallel to the first line segment, and lengths of the first and second line segments are not equal.

2. The device of claim 1 wherein the first source structure comprises a first optical cable coupled to a first light source, and the second source structure comprises a second optical cable coupled to a second light source.

3. The device of claim 1 wherein the plurality of detector structures comprises a plurality of optical detector cables coupled to a plurality of photodetectors.

4. A medical device system comprising the device of claim 1 wherein the device is a probe.

5. The device of claim 1 wherein a difference in length between the first line segment and the second line segment is at least approximately 0.03 millimeters.

6. The device of claim 1 wherein the first source structure has a diameter of approximately one millimeter, the second source structure has a diameter of approximately one millimeter, and each detector structure of the plurality of detector structures has a diameter of approximately one millimeter.

7. The device of claim 1 wherein the first line segment has a length of approximately 0.020 millimeters, and the second line segment has a length of approximately 0.24 millimeters.

8. The device of claim 1 wherein the tissue comprises human tissue.

20. The device of claim 1 wherein the received second beam of light is received by the detector arrangement after the received first beam of light.

21. The device of claim 1 wherein the received first beam of light is received by the detector arrangement after the received second beam of light.

22. The device of claim 1 wherein shapes of the first source structure, second source structure, and the detector structures are the same.

23. The device of claim 1 wherein cross-sectional areas of the first source structure, second source structure, and the detector structures are the same.

24. The device of claim 1 wherein shapes of the first source structure, second source structure, and the detector structures are circles.

25. The device of claim 1 wherein the detector arrangement comprises four detector structures having centerpoints along the first axis.

26. The device of claim 25 wherein the source and detector structures have the same cross-sectional shape and cross-sectional area.

27. The device of claim 26 wherein the source and detector structures are on the same plane.

28. The device of claim 26 wherein the source and detector structures are positioned on a bottom side of a rectangular planar surface.

29. The device of claim 28 wherein the first axis is parallel to an edge of the rectangular planar surface.

30. The device of claim 1 wherein each of the detector structures comprises optical fiber.

9. A device comprising:

a first source structure, the first source structure being positioned to provide a first beam of light;

a second source structure, the second source structure being positioned to provide a second beam of light; and

a detector arrangement, including a plurality of detector structures, each comprising optical fiber, the detector arrangement being positioned to receive the first beam of light after the first beam of light has been transmitted through a tissue, and to receive the second beam of light after the second beam of light has been transmitted through the tissue,

wherein the first source structure, the second source structure, a first detector structure, and a second detector structure define vertices of a convex quadrilateral,

a first side of the quadrilateral between the first source structure and second source structure is greater in length than a second side of the quadrilateral between the first detector structure and the second detector structure, and

a third side of the quadrilateral between the first source structure and first detector structure is greater in length than a fourth side of the quadrilateral between the second source structure and the second detector structure.

10. The device of claim 9 wherein the tissue comprises human tissue.

11. The device of claim 9 wherein the first source structure comprises a first optical cable coupled to a first light source, and the second source structure comprises a second optical cable coupled to a second light source.

12. The device of claim 9 wherein the optical fiber of the detector structures are coupled to a plurality of photodetectors.

13. A medical device system comprising the device of claim 9 wherein the device is a probe.

14. The device of claim 9 wherein the first source structure has a diameter of approximately one millimeter, the second source structure has a diameter of approximately one millimeter, and each detector structure of the plurality of detector structures has a diameter of approximately one millimeter.

31. The device of claim 9 wherein the received second beam of light is received by the detector arrangement after the received first beam of light.

32. The device of claim 9 wherein the received first beam of light is received by the detector arrangement after the received second beam of light.

33. The device of claim 9 wherein shapes of the first source structure, second source structure, and the detector structures are the same.

34. The device of claim 9 wherein cross-sectional areas of the first source structure, second source structure, and the detector structures are the same.

35. The device of claim 9 wherein shapes of the first source structure, second source structure, and the detector structures are circles.

36. The device of claim 9 wherein the detector arrangement comprises four detector structures arranged in a line.

37. The device of claim 36 wherein the first and second detector structures are at ends of the line.

38. The device of claim 37 wherein there are at most two source structures.

39. The device of claim 36 wherein the source and detector structures have the same cross-sectional shape and cross-sectional area.

40. The device of claim 36 wherein the source and detector structures are on the same plane.

41. The device of claim 36 wherein the source and detector structures are positioned on a bottom side of a rectangular planar surface, and the line is parallel to an edge of the rectangular planar surface.

15. A method of measuring oxygen saturation of a tissue comprising:

positioning a sensor head to face toward the tissue, wherein the sensor head comprises a first source structure, a second source structure, a first detector structure, and a second detector structure that define vertices of a convex quadrilateral, a first side of the quadrilateral between the first source structure and first detector structure has a different length than a second side of the quadrilateral between the second source structure and second detector structure, and the first and second detector structures comprise optical fiber;

transmitting light from a system unit through the first source structure and the second source structure into the tissue;

receiving light transmitted through the tissue and the detector structures at photodetectors in the system unit, the received light including attenuation characteristics; and

processing the received light using the system unit.

16. The method of claim 15 wherein the attenuation characteristics are caused by the difference in length between the first and second sides of the quadrilateral.

42. The device of claim 15 wherein the source and detector structures have the same cross-sectional shape and cross-sectional area.

43. The device of claim 15 wherein the sensor head further comprises third and fourth detector structures, each comprising optical fiber, arranged in a line with the first and second detector structures, and there are at most two source structures.

44. The device of claim 15 wherein the sensor head comprises at least three detectors structures, and there are more detector structures than source structures.

45. The device of claim 15 wherein the source and detector structures are positioned on a bottom side of a rectangular planar surface, the first and second detector structure are arranged in a line, where the line is parallel to a shorter edge of the rectangular planar surface.

17. A probe, the probe being adapted for use as a part of a medical device system for measuring oxygen levels in a tissue, the probe comprising:

a coupling interface, the coupling interface being adapted to allow the probe to be coupled to a plurality of light sources and a plurality of photodetectors, wherein the light sources and photodetectors are external to the probe; and

a sensor head comprising a first source structure, a second source structure, and a detector arrangement, the first source structure and the second source structure being arranged to be coupled to the plurality of light sources via the coupling interface, the detector arrangement being arranged to be coupled to the plurality of photodetectors through the coupling interface, wherein first and second detector structures of the detector arrangement and the source structures have the same cross-sectional area.

18. The probe of claim 17 wherein the first source structure and the second source structure are arranged to provide light from the plurality of light sources to the tissue, and the detector arrangement is arranged to provide the light transmitted through the tissue to the photodetectors.

19. The probe of claim 17 wherein the detector arrangement is arranged to receive the first beam of light and the second beam of light after the first beam of light and the second beam of light are transmitted through the tissue.

46. The probe of claim 17 wherein the detector arrangement comprises four detector structures, each comprising optical fiber.

47. The probe of claim 46 wherein the four detector structures are arranged in a line.

48. The probe of claim 47 wherein a first distance is between the first source structure and the first detector structure, a second distance is between the first source structure and the second detector structure, a third distance is between the second source structure and the first detector structure, a fourth distance is between the second source structure and the second detector structure, a fifth distance is between the first source structure and a third detector structure, a sixth distance is between the first source structure and a fourth detector structure, a seventh distance is between the second source structure and third detector structure, an eighth distance is between the second source structure and fourth detector structure,

the first distance is not equal to the second, third, fourth, fifth, sixth, seventh, and eighth distances, the second distance is not equal to the third, fourth, fifth, sixth, seventh, and eighth distances, the third distance is not equal to the fourth, fifth, sixth, seventh, and eighth distances, the fourth distance is not equal to the fifth, sixth, seventh, and eighth distances, the fifth distance is not equal to the sixth, seventh, and eighth distances, the sixth distance is not equal to the seventh, and eighth distances, and the seventh distance is not equal to the eighth distance.

49. The probe of claim 17 wherein the tissue is human tissue.

50. The probe of claim 17 wherein the sensor head comprises greater numbers of detector structures than source structures.

51. The probe of claim 17 wherein the first source structure, second source structure, first detector structure, and second detector structure define vertices of a convex quadrilateral.

52. The probe of claim 17 wherein a first distance between the first source structure and first detector structure is different from a second distance between the second source structure and the second detector structure.

53. The probe of claim 17 wherein a first distance between the first source structure and second source structure is greater than a second distance between the first detector structure and the second detector structure, and

a third distance between the first source structure and first detector structure is greater than a fourth distance between the second source structure and the second detector structure.

54. The probe of claim 17 wherein a bottom side of the sensor head comprises a rectangular planar surface, the source and detector structures are positioned on the bottom side, and the first and second detector structures are arranged in a line, where the line is parallel to a shorter edge of the rectangular planar surface.

55. A device comprising:

a first source structure;

a second source structure;

a first detector structure comprising optical fiber; and

a second detector structure comprising optical fiber, wherein the first source structure, second source structure, first detector structure, second detector structure define vertices of a convex quadrilateral, and

a first side of the quadrilateral between the first source structure and first detector structure is different in length from a second side of the quadrilateral between the second source structure and the second detector structure.

58. The device of claim 55 wherein the first and second source structure comprise optical fiber.

59. The device of claim 55 wherein cross-sectional shapes of the first source, second source, first detector, and second detector structures are the same.

60. The device of claim 55 wherein cross-sectional areas of the first source, second source, first detector, and second detector structures are the same.

56. A device comprising:

a first source structure;

a second source structure;

a first detector structure comprising optical fiber; and

a second detector structure comprising optical fiber, wherein the first source structure, second source structure, first detector structure, second detector structure define vertices of a convex quadrilateral, and

a first side of the quadrilateral between the first source structure and second source structure is different in length from a second side of the quadrilateral between the first detector structure and the second detector structure.

61. The device of claim 56 wherein the first and second source structure comprise optical fiber.

62. The device of claim 56 wherein cross-sectional shapes of the first source, second source, first detector, and second detector structures are the same.

63. The device of claim 56 wherein cross-sectional areas of the first source, second source, first detector, and second detector structures are the same.

57. A device comprising:

a first source structure;

a second source structure;

a first detector structure comprising optical fiber;

a second detector structure comprising optical fiber, wherein a first distance is between the first source structure and the first detector structure, a second distance is between the first source structure and the second detector structure, a third distance is between the second source structure and the first detector structure, a fourth distance is between the second source structure and the second detector structure,

the first distance is not equal to the second, third, and fourth distances, the second distance is not equal to the third and fourth distances, and the third distance is not equal to the fourth.

64. The device of claim 57 wherein the first and second source structure comprise optical fiber.

65. The device of claim 57 wherein cross-sectional shapes of the first source, second source, first detector, and second detector structures are the same.

66. The device of claim 57 wherein cross-sectional areas of the first source, second source, first detector, and second detector structures are the same.

67. The device of claim 57 wherein the first source structure, second source structure, first detector structure, and second detector structure define vertices of a convex quadrilateral.

68. The device of claim 67 wherein the first and second source structure comprise optical fiber.

69. The device of claim 67 wherein cross-sectional shapes of the first source, second source, first detector, and second detector structures are the same.

70. The device of claim 67 wherein cross-sectional areas of the first source, second source, first detector, and second detector structures are the same.

71. The device of claim 57 comprising:

a third detector structure comprising optical fiber;

a fourth detector structure comprising optical fiber, wherein a fifth distance is between the first source structure and a third detector structure, a sixth distance is between the first source structure and a fourth detector structure, a seventh distance is between the second source structure and third detector structure, an eighth distance is between the second source structure and fourth detector structure,

the first distance is not equal to the second, third, fourth, fifth, sixth, seventh, and eighth distances, the second distance is not equal to the third, fourth, fifth, sixth, seventh, and eighth distances, the third distance is not equal to the fourth, fifth, sixth, seventh, and eighth distances, the fourth distance is not equal to the fifth, sixth, seventh, and eighth distances, the fifth distance is not equal to the sixth, seventh, and eighth distances, the sixth distance is not equal to the seventh, and eighth distances, and the seventh distance is not equal to the eighth distance.