Chemically based vascular occlusion device deployment with gripping feature

• US 7,357,809 B2
• Filed: 06/30/2005
• Issued: 04/15/2008
• Est. Priority Date: 06/30/2005
• Status: Expired due to Fees

• Current Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Original Assignee: Cordis Neurovascular, Inc. (Johnson & Johnson)
• Inventors: Mitelberg, Vladimir, Jones, Donald K.
• Primary Examiner(s): Hayes; Michael J.
• Assistant Examiner(s): GETTMAN, CHRISTINA DANIELLE
• Application Number:
  US11/171,896
• Publication Number:
  US 20070005098A1
• Time in Patent Office: 1,020 Days
• Field of Search: 606/200, 606/108, 92/89, 92/90, 92/91, 92/92, 92/93
• US Class Current: 606/205
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 2017/12081 detachable by inflation

Abstract

A vascular occlusion device deployment system for placing an occlusion device at a preselected site within the vasculature of a patient. The deployment system employs a pusher including a gripper located at the distal end of the pusher to releasably retain a vascular occlusion device. The gripper is expanded by an expandable chemical reaction chamber so that the gripper releases the vascular occlusion device, thereby deploying the vascular occlusion device.

Claims

1. A vascular occlusion device deployment system, comprising:

a vascular occlusion device having a protruding portion;

a deployment unit comprising a pusher having a proximal end portion and a distal end portion;

an expandable gripper located at the distal end portion of the pusher, said gripper including an outwardly expandable gripping element for gripping the protruding portion of the vascular occlusion device;

a dispensing tube adapted to accommodate a first reactant separate from a second reactant;

an expandable reaction chamber located within said gripper, said expandable reaction chamber having an expandable interior cavity accessible through an opening, said dispensing tube being fluid in communication with said opening into the expandable reaction chamber; and

said chamber expands upon a reaction of at least said first reactant and said second reactant within said closed interior cavity of said chamber whereby the expansion of the chamber causes the gripper to outwardly expand, releasing the protruding portion of the vascular occlusion device.

2. The deployment system of claim 1 wherein the expandable reaction chamber comprises a polymeric material.

3. The deployment system of claim 1 wherein the gripping elements comprise a plurality of jaws.

4. The deployment system of claim 1 wherein the first reactant comprises a mixture of cyanoacrylate monomer and ethanol, and the second reactant comprises a mixture of ethanol and N,N-Dirnethyl-p-toluidine.

5. The deployment system of claim 1 wherein the first and second reactants produce a polycyanoacrylate foam when mixed together.

6. The deployment system of claim 1 wherein said dispensing tube includes a first dispensing unit for dispensing the first reactant into the cavity of said expandable reaction chamber, and a second dispensing unit for dispensing the second reactant into the cavity of the reaction chamber.

7. The deployment system of claim 1 wherein the first dispensing unit comprises a first lumen and the second dispensing unit comprises a second lumen.

8. The deployment system of claim 7 wherein the first and second lumens extend through the pusher.

9. The deployment system of claim 7 wherein the first lumen and the second lumen comprise said dispensing tube which is a dual lumen dispensing unit.

10. The deployment system of claim 7 wherein the first lumen and the second lumen are plunger operated.

11. A vascular occlusion device deployment system for deploying a vascular occlusion device at a preselected site within the vasculature of a patient, comprising:

a deployment unit comprising a pusher having a proximal end portion and a distal end portion;

an expandable gripper located at the distal end portion of the pusher, said gripper including an outwardly expandable gripping element for gripping a vascular occlusion device;

an expandable reaction chamber located for engagement with said gripper, said reaction chamber having an expandable interior cavity that has a first volume and a second volume that is greater than said first volume;

a first dispensing unit including a first reactant, said first dispensing unit opening into the expandable reaction chamber;

a second dispensing unit including a second reactant, said second dispensing unit opening into the expandable reaction chamber; and

said expandable reaction chamber receives the first reactant from said first dispensing unit and the second reactant from said second dispensing unit to produce a product within the expandable reaction chamber that has a volume larger than the combined volume of said first and second reactants prior to mixing, said larger volume of the product causing the expandable reaction chamber to expand outwardly to said second volume and cause the gripping element to expand outwardly for releasing the vascular occlusion device therefrom.

12. The deployment system of claim 11 wherein the expandable reaction chamber comprises an elastomeric polymer material.

13. The deployment system of claim 11 wherein the gripper element comprises a plurality of expandable jaws.

14. The deployment system of claim 11 wherein the first reactant comprises a mixture of cyanoacrylate monomer and ethanol, and the second reactant comprises a mixture of ethanol and N,N-Dimethyl-p-toluidine.

15. The deployment system of claim 11 wherein the first and second reactants produce a polycyanoacrylate foam when mixed together.

16. The deployment system of claim 11 wherein the first dispensing unit comprises a first a lumen having said first reactant therein and the second dispensing unit comprises a second lumen having said second reactant therein.

17. The deployment system of claim 16 wherein the first and second lumens extend through the pusher.

18. A method for deployment of a vascular occlusion device at a preselected location within the vasculature of a patient, comprising:

providing a deployment unit comprising a pusher member having a gripper located at a distal end of the pusher member, said gripper having an expandable gripper element for gripping a vascular occlusion device and an expandable reaction chamber disposed within said gripper;

gripping a protruding portion of a vascular occlusion device with said gripper;

guiding the vascular occlusion device to a preselected location with in the vasculature of a patient with said pusher;

mixing at least a first reactant and a second reactant within the interior of the expandable reaction chamber to provide a product having a volume greater than the combined volume of the first and second reactants, said product expanding the expandable reaction chamber; and

expanding the gripping elements under the force of the expanding reaction chamber, thereby releasing the protruding portion of the vascular occlusion device.

19. The method of claim 18 further including pushing the coil out of the gripper under the force of the expanding reaction chamber.

20. The method of claim 18 wherein the mixing of at least said first reactant and said second reactant comprises dispensing a first reactant into the cavity through a first dispensing lumen and dispensing the second reactant into the cavity through a second dispensing lumen.

21. The method of claim 18 wherein the mixing of at least said first reactant and said second reactant comprises mixing a cyanoacrylate monomer and ethanol, and a mixture of ethanol and N,N-Dimethyl-p-toluidine.