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Prevention of diabetes through induction of immunological tolerance

  • US 7,361,333 B2
  • Filed: 09/12/2003
  • Issued: 04/22/2008
  • Est. Priority Date: 10/26/1995
  • Status: Expired due to Fees
First Claim
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1. A method of preventing onset of Type I diabetes in a mammal predisposed to Type I diabetes, comprising implanting a dose of insulin-producing cells encapsulated in a biologically-compatible membrane into an implantation site in said mammal prior to onset of Type I diabetes, wherein said dose is at least one order of magnitude less than that necessary to achieve normoglycemia in a mammal of the same species with type I diabetes.

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