Dual electrode system for a continuous analyte sensor
First Claim
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1. An analyte sensor configured for insertion into a host for measuring an analyte in the host, the sensor comprising:
- a first working electrode comprising a first electroactive surface disposed beneath an active enzymatic portion of a membrane;
a second working electrode comprising a second electroactive surface disposed beneath an inactive-enzymatic or non-enzymatic portion of a membrane; and
an electrical insulator located between the first working electrode and the second working electrode, wherein the sensor comprises a physical diffusion barrier configured to structurally block a substantial amount of diffusion of at least one of an analyte and a co-analyte between the first electroactive surface and the second eleetroactive surface by a structure that protrudes from a plane that intersects both the first electroactive surface and the second eleetroactive surface, wherein the structure that protrudes comprises the electrical insulator and/or an electrode.
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Abstract
Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
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Citations
36 Claims
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1. An analyte sensor configured for insertion into a host for measuring an analyte in the host, the sensor comprising:
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a first working electrode comprising a first electroactive surface disposed beneath an active enzymatic portion of a membrane; a second working electrode comprising a second electroactive surface disposed beneath an inactive-enzymatic or non-enzymatic portion of a membrane; and an electrical insulator located between the first working electrode and the second working electrode, wherein the sensor comprises a physical diffusion barrier configured to structurally block a substantial amount of diffusion of at least one of an analyte and a co-analyte between the first electroactive surface and the second eleetroactive surface by a structure that protrudes from a plane that intersects both the first electroactive surface and the second eleetroactive surface, wherein the structure that protrudes comprises the electrical insulator and/or an electrode. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. An analyte sensor configured for insertion into a host for measuring an analyte in the host, the sensor comprising:
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a first working electrode comprising a first electroactive surface disposed beneath an active enzymatic portion of a membrane system; a second working electrode comprising a second electroactive surface disposed beneath an inactive-enzymatic or non-enzymatic portion of the membrane system; and an insulator located between the first electroactive surface and the second electroactive surface, wherein the membrane system is configured to substantially block diffusion of at least one of an analyte and a co-analyte between the first electroactive surface and the second electroactive surface by a discontinuity of the membrane system between the first electroactive surface and the second electroactive surface. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. An analyte sensor configured for insertion into a host for measuring an analyte in the host, the sensor comprising:
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a first working electrode comprising a first electroactive surface disposed beneath an active enzymatic portion of a membrane; a second working electrode comprising a second electroactive surface disposed beneath an inactive-enzymatic or non-enzymatic portion of a membrane; and an insulator located between the first electroactive surface and the second electroactive surface, wherein the sensor comprises a diffusion barrier configured to substantially block diffusion of at least one of an analyte and a co-analyte between the first electroactive surface and the second electroactive surface wherein the diffusion barrier comprises a temporal diffusion barrier configured to block or avoid a substantial amount of diffusion or reaction of at least one of the analyte and the co-analyte between the first and second electroactive surfaces. - View Dependent Claims (34, 35, 36)
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Specification