Automatic commutations of AAI/DDD mode in the presence of paroxystic AVB in an active implantable medical device, in particular a cardiac pacemaker

• US 7,366,566 B2
• Filed: 12/22/2004
• Issued: 04/29/2008
• Est. Priority Date: 12/29/2003
• Status: Active Grant

• Current Assignee: Ela Medical S.A. (LivaNova Plc)
• Original Assignee: Sorin CRM SAS
• Inventors: Amblard, Amel, Henry, Christine, Limousin, Marcel
• Primary Examiner(s): Evanisko; George R.
• Assistant Examiner(s): STOKLOSA, JOSEPH A
• Application Number:
  US11/022,326
• Publication Number:
  US 20050143780A1
• Time in Patent Office: 1,224 Days
• Field of Search: 607/9
• US Class Current: 607/9
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

A device including circuits able to control the switching of a AAI mode in a DDD mode, and conversely the return of DDD mode to AAI mode, according to predetermined criteria of detection of atrio-ventricular block (AVB) of the first, second, or third degree and of ventricular pause. The device includes moreover circuits for detecting state, able to diagnose at least a specific temporary state of the patient, in particular a state of effort or sleep, and the circuits for mode switching operate in response to these circuits for detecting state to modify selectively, for the length of time when the aforementioned state is diagnosed, the criteria of switching from AAI mode towards DDD mode and/or the criteria of return to AAI mode, and/or the criteria of final commutation in DDD mode.

Claims

1. An active implantable medical device comprising:

means for detecting spontaneous atrial and ventricular events;

means for ventricular and atrial stimulation;

means for operating the device in AAI mode with ventricular detection;

means for operating the device in DDD mode;

means for mode switching,

wherein said means for mode switching further comprises means for controlling switching from AAI mode to DDD mode when at least one of the following conditions, each of which is checked by the means for mode switching, is fulfilled;

a) the number of atrial events followed by a ventricular detection occurring after a delay longer than a first reference duration exceeds a first predetermined number;

b) the number of atrial events not followed by a ventricular detection exceeds a second predetermined number among a third given number of consecutive atrial events;

c) the number of consecutive atrial events not followed by a ventricular detection exceeds a fourth predetermined number; and

d) the interval separating two ventricular events exceeds a second reference duration; and

wherein said means for mode switching further comprises means for controlling the return from the DDD pacing mode to AAI pacing mode according to a criteria;

means for state detecting, further comprising means for diagnosing a temporary specific state of a patient carrying the device, including a phase of suspicion of disorder of the atrial rate of the patient and at least one of a phase of effort and a phase of sleep of the patient; and

wherein the mode switching means further comprises means for suspending, when said means for state detecting diagnoses a phase of suspicion of disorder of the atrial rate of the patient, the checking of the conditions a) to c), while maintaining the checking of the condition d), for a length of time at least equal to a duration of the phase of suspicion of disorder of the atrial rate of the patient.

2. The device of claim 1, wherein the means for state detecting further comprises means for diagnosing a phase of cardiac decompensation of the patient.

3. The device of claim 1, wherein the means for mode switching includes a grid of counters assigned respectively to the conditions a) to d) and to each of the diagnosed temporary specific states, the corresponding counter being incremented when the respective condition is fulfilled and when the respective state is diagnosed.

4. The device of claim 3, wherein the mode switching means further comprises a grid of thresholds homologous with the grid of counters, each threshold being programmable, and are able to force the switching from AAI mode towards DDD mode when at least one of the thresholds is reached by the corresponding counter.

5. The device of claim 1, wherein the means for mode switching further comprises means, operating in response to the means for state detecting, for modifying the criteria of the return to AAI mode after switching towards DDD mode during the time when a phase of effort or sleep is diagnosed.

6. The device of claim 5, wherein the means for mode switching further comprises means, operating in response to the means for state detecting, for temporarily suspending any return to AAI mode after switching towards DDD mode during the time when a phase of effort or sleep is diagnosed.

7. The device of claim 5, wherein the means for mode switching further comprises means, operating in response to the means for state detecting, for temporarily modifying in a restrictive direction the criteria of return to AAI mode after switching towards DDD mode during the time when the phase of effort or sleep is diagnosed.

8. The device of claim 7, wherein the means for mode switching further comprises means operating in response to the means for state detecting, for controlling without delay the return to AAI mode after switching towards DDD mode after the end of the phase of effort or sleep.

9. The device of claim 7, wherein the means for mode switching further comprises means, operating in response to the means for state detecting, for temporarily modifying in an extensive direction the criteria of return to AAI mode after switching towards DDD mode after the end of the phase of effort or sleep.

10. The device of claim 1, further comprising:

a criteria of durable commutation to DDD mode; and

wherein the means for mode switching further comprises means for durable commutation, able to inhibit the return of DDD mode to AAI mode and to force the operating mode to DDD mode in function of the criteria of durable commutation to DDD mode.

11. The device of claim 10, wherein the means for durable commutation further comprises means for selectively incrementing counters, corresponding to the conditions a) to d), when the respective condition is fulfilled, wherein the means for mode switching inhibits the return of DDD mode to AAI mode and forces the operating mode to DDD mode when the counters reach a predetermined configuration of counting.

12. The device of claim 11, wherein the means for durable commutation is able to inhibit the incrementing of the counters when one of the conditions a) to c) is fulfilled while authorizing the incrementing when the condition d) is fulfilled, in the event of commutation consecutive to a diagnosis of phase of effort or sleep.

13. The device of claim 11, wherein the means for durable commutation is able to inhibit the incrementing of the counters in the event of the occurrence of a commutation separated from the preceding commutation by a number of cycles in AAI mode lower than a fifth predetermined number.

14. The device of claim 10, wherein the means for durable commutation is able to inhibit the return of DDD mode to AAI mode and to force the operating mode to DDD mode when the number of commutations of AAI mode towards DDD mode is higher than a sixth number predetermined over a first predetermined temporal period.

15. The device of claim 10, wherein the means for durable commutation is able to inhibit the return of DDD mode to AAI mode and to force the operating mode to DDD mode when the percentage of ventricular events stimulated over a second predetermined temporal period is higher than a first predetermined threshold.

16. The device of claim 10, wherein the means for durable commutation further comprises means for controlling the return to the operating mode in AAI mode at the end of each phase of sleep.

17. The device of claim 11, wherein the means for durable commutation further comprises means for reinitialing the counters at the end of each phase of sleep.

18. The device of claim 10, further comprising:

a criteria of final commutation in DDD mode; and

wherein the means for mode switching further comprises means for final commutation, able to prohibit the return from DDD mode to AAI mode and to impose an operating DDD mode until reprogramming of the device, as a function of the criteria of final commutation in DDD mode.

19. The device of claim 18, wherein the means for final commutation is able to prohibit the return from DDD mode to AAI mode and to impose an operating DDD mode until reprogramming of the device when a number of durable commutations of AAI mode towards DDD mode is higher than a seventh predetermined number over a third predetermined temporal period.

20. The device of claim 18, wherein the means for final commutation is able to prohibit the return of DDD mode to AAI mode and to impose an operating DDD mode until reprogramming of the device when a percentage of ventricular events stimulated over a fourth predetermined temporal period is greater than a second predetermined threshold.

21. The device of claim 1, wherein the means for mode switching reduces a first duration of reference during a time when a phase of effort is diagnosed.

22. The device of claim 21, wherein the means for mode switching reduces a first duration of reference to a value which is an inverse function of a frequency of stimulation.

23. The device of claim 22, wherein the inverse function of a frequency of stimulation is a decreasing monotonic function from a base frequency of stimulation to a maximum frequency of stimulation.

24. The device of claim 22, wherein the inverse function of a frequency of stimulation is a decreasing monotonic function between a low frequency, higher than a base frequency of stimulation, and a high frequency, higher than a maximum frequency of stimulation, and a constant function below the base frequency of stimulation and above the maximum frequency of stimulation.

25. The device of claim 1, further comprising means for differentiated recording of cardiac data, further comprising means for memorizing specifically predetermined data during a time when a temporary specific state is diagnosed.

26. The device of claim 25, wherein the predetermined data memorized by the means for differentiated recording includes values of durations of atrio-ventricular conduction.

27. The device of claim 25, wherein the predetermined data memorized by the means for differentiated recording includes each duration of an episode during which commutations follow one another separated from each other by a number of cycles in AAI mode lower than a fifth predetermined number.