Systems and methods for treating movement disorders

• US 7,369,896 B2
• Filed: 10/24/2003
• Issued: 05/06/2008
• Est. Priority Date: 10/24/2002
• Status: Expired due to Fees

• Current Assignee: Lockheed Martin Corporation (Martin Marietta Corporation)
• Original Assignee: Lockheed Martin Corporation (Martin Marietta Corporation)
• Inventors: Gesotti, Phillip E.
• Primary Examiner(s): Evanisko; George R.
• Assistant Examiner(s): KAHELIN, MICHAEL WILLIAM
• Application Number:
  US10/693,792
• Publication Number:
  US 20040088025A1
• Time in Patent Office: 1,656 Days
• Field of Search: 607/48, 607/49, 434/255, 128/905, 340/573.1
• US Class Current: 607/49
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance

Abstract

Movement timing stimulator systems and methods that aid in the relief of the symptoms of neurological movement disorders are provided. In one embodiment, a method of improving a patient'"'"'s gait is provided. The method includes producing a plurality of stimulation prompts at a plurality of stimulation points using multiple stimulation channels. The plurality of stimulation points is located symmetrically on each leg. The method further includes applying the plurality of stimulation prompts in a timed periodic fashion across the plurality of stimulation points and activating a return electrode whenever one of the multiple stimulation channels on an associated leg is active. The plurality of stimulation prompts are not synchronized with the patient'"'"'s gait. Each of the multiple stimulation channels is associated with a stimulation electrode at one of the plurality of stimulation points.

Claims

1. A method of improving a patient'"'"'s gait, the method comprising:

producing a plurality of stimulation prompts at a plurality of stimulation points using multiple stimulation channels;

wherein the plurality of stimulation points are located symmetrically on each leg;

applying the plurality of stimulation prompts in a timed periodic fashion across the plurality of stimulation points;

wherein the plurality of stimulation prompts are not synchronized with the patient'"'"'s gait and do not force muscle contraction;

wherein each of the multiple stimulation channels is associated with a stimulation electrode at one of the plurality of stimulation points; and

activating a return electrode whenever one of the multiple stimulation channels on an associated leg is active.

2. The method of claim 1, wherein the plurality of stimulation prompts each have a stimulation pulse period of approximately 14 milliseconds.

3. The method of claim 1, wherein the plurality of stimulation points are associated with a plurality of muscles and contraction of the plurality of muscles is not coincident with the corresponding stimulation prompt.

4. The method of claim 1, further comprising setting the intensity of the plurality of stimulation prompts below motor threshold for muscles associated with the plurality of stimulation points.

5. The method of claim 1, further comprising setting the amplitude of the plurality of stimulation prompts below motor thresholds to facilitate central nervous system induced contractions of muscles associated with the plurality of stimulation points.

6. The method of claim 1, further comprising setting the duration of the plurality of stimulation prompts to facilitate central nervous system induced fused contractions of muscles associated with the plurality of stimulation points.

7. The method of claim 1, wherein producing a plurality of stimulation prompts at a plurality of stimulation points using multiple stimulation channels comprises producing stimulation prompts in the vicinity of motor points of the anterior tibial muscle, gastrocnemius muscle, and rectus femoris muscle on each leg.

8. The method of claim 1, wherein producing a plurality of stimulation prompts comprises sequentially producing stimulation prompts at stimulation points near the anterior tibial muscle on the right leg, the gastrocnemius muscle on the right leg, the anterior tibial muscle on the left leg, the gastrocnemius muscle of the left leg, the rectus femoris muscle of the right leg and the rectus femoris muscle of the left leg.

9. The method of claim 1, wherein each stimulation channel is individually associated with a cue clock.

10. The method of claim 9, wherein a first channel is associated with a first cue clock and stimulation pulses for an associated stimulation electrode are active when the first cue clock is active.

11. The method of claim 10, wherein the first cue clock is active during a first cue interval.

12. The method of claim 10, wherein a second channel is associated with a second cue clock and stimulation pulses for an associated stimulation electrode are active when the second cue clock is active.

13. The method of claim 12, wherein the second cue clock is active during a second half of a second cue interval.

14. The method of claim 11, wherein the first cue interval is approximately 0.4 seconds.

15. The method of claim 13, wherein the second cue interval is approximately 0.4 seconds.

16. The method of claim 12, wherein a third channel is associated with a third cue clock and stimulation pulses for an associated stimulation electrode are active when the third cue clock is active.

17. The method of claim 16, wherein the third cue clock is active during a second quarter of the first cue interval.

18. The method of claim 16, wherein the first, second and third cue clocks are associated with stimulation electrodes located on one leg.

19. The method of claim 18, wherein fourth, fifth and sixth channels are associated with fourth, fifth and sixth cue clocks, wherein the fourth, fifth and sixth cue clocks are active during the same portion of opposite cue intervals to the first, second and third cue clocks.

20. The method of claim 2, wherein the stimulation pulse has a pulse width of approximately 400 microseconds.

21. The method of claim 1, further comprising applying stimulation pulses for each of the multiple stimulation channels in a bi-phasic manner.

22. The method of claim 1, further comprising time division multiplexing stimulation pulses for each of the multiple stimulation channels.

23. The method of claim 1, wherein stimulation current for the stimulation prompts is approximately 10 milliamps.

24. A method of reducing habituation in improving a patient'"'"'s gait, the method comprising:

producing a plurality of stimulation prompts at a plurality of stimulation points using multiple stimulation channels;

wherein the plurality of stimulation points are located symmetrically on each leg;

applying the plurality of stimulation prompts in a timed periodic fashion across the plurality of stimulation points;

wherein the plurality of stimulation prompts are not synchronized with the patient'"'"'s gait and do not force muscle contraction;

wherein each of the multiple stimulation channels is associated with a stimulation electrode at one of the plurality of stimulation points; and

activating a return electrode whenever one of the multiple stimulation channels on an associated leg is active;

linearly changing a pulse period for the plurality of stimulation prompts.