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Valved prosthesis with porous substrate

  • US 7,371,258 B2
  • Filed: 10/26/2001
  • Issued: 05/13/2008
  • Est. Priority Date: 10/26/2001
  • Status: Expired due to Fees
First Claim
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1. An implantable prosthesis comprising:

  • at least one occluder, wherein the at least one occluder comprises a rigid material with pores formed in the rigid material, wherein the rigid material is selected from the group consisting of metals, carbonaceous solids, polymers, and ceramics; and

    a filler comprising a hydrogel or a structural protein or a bioactive agent or mixtures thereof, the filler being located within the pores, wherein said rigid porous material with the filler presents a smoother surface for fluid flow than pores without filler and wherein the filler prevents back flow of fluid through the pores of the occluder.

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