Infusion pump and method for use

• US 7,374,556 B2
• Filed: 01/31/2006
• Issued: 05/20/2008
• Est. Priority Date: 07/19/2002
• Status: Expired due to Fees

• Current Assignee: Tandem Diabetes Care Incorporated
• Original Assignee: Tandem Diabetes Care
• Inventors: Mallett, Scott
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US11/343,817
• Publication Number:
  US 20060150748A1
• Time in Patent Office: 840 Days
• Field of Search: 604/141, 604/140, 604/153, 604 65- 67, 604131-133, 604143-145, 604/151, 604890- 1, 604/891.1, 604 27- 31, 604503-505, 604/93.01, 128/DIG.12, 128/DIG.13
• US Class Current: 604/132
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/145 using pressurised reservoirs, e.g. pressurised by means of pistons
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure
• CPC Class Codes: A61M 5/16809 by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: G01F 1/34 by measuring pressure or differential pressure
• CPC Class Codes: G01F 11/04 of the free-piston type
• CPC Class Codes: Y10T 137/0318 Processes
• CPC Class Codes: Y10T 137/85986 Pumped fluid control

Abstract

A fluid dispensing system provides a non-contact method of monitoring the change in the fluid volume over time. This approach avoids the use of probes or sensors that come into direct contact with the fluid to be dispensed. The system comprises an apparatus comprising three chambers. The first chamber has a fixed volume and contains a pressurized gas. A solenoid valve is used to control the flow of gas from the first chamber into the second. The second chamber is sealed so that the combined mass of air in the first and second chambers remains fixed. The third chamber is adjacent to the second and contains medication in the form of incompressible fluid that is to be administered to a human or animal subject via a suitable delivery port. A piston is disposed between the second and third chambers and is movable responsive to the flow of gas into the second chamber to dispense fluid from the third chamber as desired. By sensing the pressure in the first and second chambers at any point in time, a processor is programmed to calculate the flow rate or dispensed volume of the fluid being delivered using principles derived from the Ideal Gas Law.

Claims

1. A device for delivering controllable quantities of a fluid comprising:

(a) a first chamber having a fixed volume arid holding a gas;

(b) a second chamber;

(c) a device for transferring the gas from the first chamber to the second chamber;

(d) a first sensor for sensing pressure in at least one of the first chamber and second chamber;

(e) a second sensor for sensing the differential pressure between the first chamber and the second chamber;

(f) a space within the device that contains a fluid;

(g) a port for delivery of the fluid; and

(h) a processor for determining the volume of the second chamber;

wherein each sensor is never in contact with the fluid in the space.

2. The device of claim 1, further comprising a valve to communicate pressure between the first chamber and the second chamber.

3. The device as recited in claim 1, wherein the first sensor sequentially senses pressure in the first chamber and the second chamber.

4. The device as recited in claim 1, wherein the processor determines the volume of the second chamber using pressure data obtained from at least one of the sensors and the fixed volume of the first chamber.

5. The device as recited in claim 4, wherein the processor determines the rate of flow by determining the change in volume of the second chamber over a predetermined period of rime and deriving the change in volume of the space over the same period of time therefrom.

6. The device as recited in claim 1, wherein the processor is adapted to repeatedly determine the rate of flow of the fluid in order to monitor the dispense rate of the fluid and a remaining quantity of fluid in the space.

7. A device for delivering controllable quantities of fluid comprising:

(a) a plurality of chambers further comprising at least;

(i) a first chamber having a fixed volume for holding a gas; and

(ii) a second chamber;

(b) a device for transferring the gas from the first chamber to the second chamber;

(c) a first sensor for sequentially sensing pressure in the first and second chambers;

(d) a space within the device that contains a fluid and a port for delivery of the fluid; and

(e) a processor for determining the volume of the second chamber;

wherein the sensor is never in contact with the fluid in the space.

8. The device of claim 7, further comprising a valve to communicate pressure between the first chamber and the second chamber.

9. The device recited in claim 7, further comprising a second sensor for sensing the differential pressure between the first chamber and the second chamber.

10. The device as recited in claim 7, wherein the processor determines the volume of the second chamber using pressure data obtained from the first sensor and the fixed volume of the first chamber.

11. The device as recited in claim 10, wherein the processor determines the rate of flow by determining the change in volume of the second chamber over a predetermined period of time and deriving the change in volume of the space over the same period of time therefrom.

12. The device as recited in claim 7, wherein the processor is adapted to repeatedly determine the rate of flow of the fluid in order to monitor the dispense rate of the fluid and a remaining quantity of fluid in the space.

13. A device for delivering controllable quantities of a fluid, comprising, in combination:

(a) a first chamber having a fixed volume for holding a gas;

(b) a second chamber;

(c) a device for transferring the gas from the first chamber to the second chamber;

(d) a third chamber for holding a fluid, wherein a combined volume of the second and third chambers is fixed;

(e) a movable boundary disposed between the second and third chambers;

(f) a dispensing port for dispensing the fluid from the third chamber;

(g) a pressure sensing apparatus; and

(h) a processor for determining the volume of the second chamber;

wherein die pressure sensing apparatus is selected from the group of pressure sensing apparatuses containing;

(i) a first sensor for sensing pressure in at least one of the first chamber and second chamber, and a second sensor for sensing the differential pressure between the first chamber and the second chamber;

(ii) a first sensor for sequentially sensing pressure in the first chamber and the second chamber; and

(iii) a first sensor for sequentially sensing pressure in the first chamber and the second chamber, and a second sensor for sensing the differential pressure between the first chamber and the second chamber.

14. The device of claim 13, further comprising a valve to communicate pressure between the first chamber and the second chamber.

15. The device as recited in claim 13, wherein the processor determines the volume of the second chamber using pressure data obtained from the sensing apparatus and the fixed volume of the first chamber.

16. The device as recited in claim 15, wherein the processor determines the rate of flow by determining the change in volume of the second chamber over a predetermined period of time arid deriving the change in volume of the third chamber over the same period of time therefrom.

17. The device as recited in claim 13, wherein the processor is adapted to repeatedly determine the rate of flow of the fluid in order to monitor the dispense rate of the fluid and a remaining quantity of fluid in the third chamber.

18. The device as recited in claim 13, further comprising solenoid communication valves.

19. The device as recited in claim 13, further comprising at least a luer connector.