Endo-cavity focused ultrasound transducer

• US 7,377,900 B2
• Filed: 06/02/2003
• Issued: 05/27/2008
• Est. Priority Date: 06/02/2003
• Status: Expired due to Term

• Current Assignee: InSightec Ltd.
• Original Assignee: Insightec-Image-Guided Treatment Limited
• Inventors: Kopelman, Doron, Vitek, Shuki, Medan, Yoav, Maor, Dov
• Primary Examiner(s): CASLER, BRIAN L
• Application Number:
  US10/452,061
• Publication Number:
  US 20040242999A1
• Time in Patent Office: 1,821 Days
• Field of Search: 600/439, 600/459, 600/471, 601 2- 4, 606/1, 604/22
• US Class Current: 600/439
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 17/2251 characterised by coupling elements between the apparatus, e.g. shock wave apparatus or locating means, and the patient, e.g. details of bags, pressure control of bag on patient
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/22028 arrays, e.g. phased arrays
• CPC Class Codes: A61B 2017/2253 using a coupling gel or liquid
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

An apparatus for delivering acoustic energy to a target site adjacent a body passage includes first and second elongate members, each carrying one or more transducer elements on their distal ends. The first and/or second elongate members include connectors for securing the first and second elongate members together such that the transducer elements together define a transducer array. The first and second elongate members are introduced sequentially into a body passage until the transducer elements are disposed adjacent a target site. Acoustic energy is delivered from the transducer elements to the target site to treat tissue therein. In another embodiment, the apparatus includes a tubular member and an expandable structure carrying a plurality of transducer elements. The structure is expanded between a contracted configuration during delivery and an enlarged configuration when deployed for delivering acoustic energy to a target site adjacent the body passage.

Claims

1. A method for delivering acoustic energy into a target tissue region adjacent a body passage, the method comprising:

introducing a first member into the body passage until a first transducer carried by the first member is disposed adjacent the target tissue region;

introducing a second member into the body passage until a second transducer carried by the second member is disposed adjacent the first transducer;

detachably coupling the first and the second transducers to each other to at least partially form a transducer array; and

delivering acoustic energy from the first and second transducers towards the target tissue region to treat tissue therein.

2. The method of claim 1, further comprising securing the first member to the second member to substantially maintain the first and second transducers relative to one another.

3. The method of claim 1, further comprising introducing an expandable member into the body passage;

introducing the first and the second transducers within am interior or the expandable member; and

expanding the expandable member until it substantially engages a wall of the body passage.

4. The method of claim 3, wherein fluid is delivered into the interior of the expandable member to expand the expandable member until it substantially engages a wall of the body passage, the fluid acoustically coupling the first and second transducers with the wall of the body passage.

5. The method of claim 1, wherein at least one of the first and second transducers comprises a plurality or transducer elements, and wherein acoustic energy is delivered from the plurality of transducer elements towards the target region to treat tissue therein.

6. The method of claim 1, further comprising introducing a third member into the body passage until a third transducer carried by the third member is disposed adjacent the first and second transducer elements, and wherein acoustic energy is delivered from the third transducer towards the target region in conjunction with the first and second transducers.

7. The method of claim 1, wherein the body passage comprises a natural body lumen.

8. The method of claim 1, further comprising creating the body passage through tissue to a location adjacent the target tissue region.

9. Apparatus for treating internal body tissue, comprising:

a first elongate member sized and shaped for insertion into a body passage, and including a first transducer carried on a distal end of the first member distal end;

a second elongate member sized and shaped for insertion into a body passage, and including a second transducer carried on a distal end of the second member; and

a controller operatively connected to the first and second transducers,

wherein the first and second members are configured for separate insertion into a same or differing body passage, whereby the first and second transducers may form respective active transducer elements of an array coordinated by the controller to deliver focused acoustic energy to treat tissue in a target tissue region located adjacent the respective same or differing body passages.

10. The apparatus of claim 9, further comprising one or more additional elongate members, each having a distal end sized and shaped for insertion into a body passage, and each carrying an additional transducer on its distal end, wherein the one or more additional members are each configured for separate insertion into a same or differing body passage as the first and second members, such that the transducers carried by the one or more additional members are a part of the transducer array.

11. The apparatus of claim 9, further comprising a connector for substantially securing the first and second members relative to one another.

12. The apparatus of claim 11, wherein the connector comprises one or more cooperating hooks and openings on the first and second elongate members.

13. The apparatus of claim 9, the first and second members each comprising one or more leads extending from the respective first and second transducers for coupling the first and second transducer elements to at least one of a driver and a controller.

14. The apparatus of claim 9, further expanding an expandable member comprising an interior within which the respective first and second member distal ends may be positioned, and an inlet communicating with the interior for introducing fluid into the interior, that expandable member being expandable from a collapsed configuration to facilitate insertion into a body passage to an enlarged configuration for substantially engaging tissue surrounding the body passage when fluid is introduced into the interior.

15. The apparatus of claim 14, further comprising a source of fluid coupled to the inlet for delivering fluid into the interior of the expandable member.

16. The apparatus of claim 14, wherein the expandable member comprises a material having an acoustic impedance that corresponding substantially to an acoustic impedance of the surrounding tissue.

17. The apparatus of claim 9, wherein the traducer array has a cross section between about ten and seventy millimeters (10-70 mm).

18. The apparatus of claim 9, wherein the first and second elongate members each carries a plurality of transducer elements on its respective distal end.

19. A method for treating internal body tissue, comprising:

introducing a first elongate member into a body passage, the first elongate member carrying one at more transducer elements operatively connected to a controller;

introducing a second elongate member into a same or different body passage, the second elongate member carrying one or more additional transducer elements operatively connected to the controller; and

simultaneously delivering acoustic energy, coordinated by the controller, from at least one transducer element carried on the first elongate member and from at least one transducer element carried an the second elongate member towards a target tissue region to treat tissue therein.

20. The method of claim 19, further comprising tracking a relative position of the respective transducer elements carried on the first and second elongate members.

21. The method of claim 19, wherein the first and second elongate members are introduced into the same body passage.

22. The method of claim 19, wherein the first elongate member is introduced into a first body passage, and the second elongate member is introduced into a second body passage.