Hybrid imaging method to monitor medical device delivery and patient support for use in the method

• US 7,379,769 B2
• Filed: 08/12/2004
• Issued: 05/27/2008
• Est. Priority Date: 09/30/2003
• Status: Active Grant

• Current Assignee: Invivo Corporation (Koninklijke Philips N.V.)
• Original Assignee: Sunnybrook Health Sciences Centre
• Inventors: Piron, Cameron Anthony, Luginbuhl, Christopher Alexander, Plewes, Donald B.
• Primary Examiner(s): Winakur; Eric F.
• Assistant Examiner(s): ROZANSKI, MICHAEL T
• Application Number:
  US10/916,738
• Publication Number:
  US 20050080333A1
• Time in Patent Office: 1,384 Days
• Field of Search: 600/411, 600/417, 600/415, 606/130, 378/87, 560/0, 560/1, 561/5
• US Class Current: 600/415
• CPC Class Codes: A61B 10/0233 Pointed or sharp biopsy instruments
• CPC Class Codes: A61B 2017/3411 with a plurality of holes, e.g. holes in matrix arrangement
• CPC Class Codes: A61B 2017/3413 guided by ultrasound
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 8/0825 for diagnosis of the breast, e.g. mammography
• CPC Class Codes: A61B 8/0833 involving detecting or locating foreign bodies or organic structures
• CPC Class Codes: A61B 8/0841 for locating instruments
• CPC Class Codes: A61B 8/406 using means for diagnosing suspended breasts
• CPC Class Codes: A61B 8/4245 involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
• CPC Class Codes: A61B 8/4416 related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
• CPC Class Codes: A61B 8/5238 for combining image data of patient, e.g. merging several images from different acquisition modes into one image for image registration algorithms G06T7/30
• CPC Class Codes: A61B 90/10 for stereotaxic surgery, e.g. frame-based stereotaxis
• CPC Class Codes: A61B 90/11 with guides for needles or instruments, e.g. arcuate slides or ball joints
• CPC Class Codes: A61B 90/14 Fixators for body parts, e.g. skull clamps; Constructional details of fixators, e.g. pins
• CPC Class Codes: A61B 90/17 for soft tissue, e.g. breast-holding devices
• CPC Class Codes: G01S 7/52049 using correction of medium-induced phase aberration

Abstract

This invention discloses a method and apparatus to deliver medical devices to targeted locations within human tissues using imaging data. The method enables the target location to be obtained from one imaging system, followed by the use of a second imaging system to verify the final position of the device. In particular, the invention discloses a method based on the initial identification of tissue targets using MR imaging, followed by the use of ultrasound imaging to verify and monitor accurate needle positioning. The invention can be used for acquiring biopsy samples to determine the grade and stage of cancer in various tissues including the brain, breast, abdomen, spine, liver, and kidney. The method is also useful for delivery of markers to a specific site to facilitate surgical removal of diseased tissue, or for the targeted delivery of applicators that destroy diseased tissues in-situ.

Claims

1. An apparatus used in conjunction with imaging and intervention for supporting a patient and transporting the patient to an MR imaging system having a bore, the apparatus comprising:

a transport stretcher including a wheeled base and a pedestal supported on the wheeled base, an upper surface of the pedestal being offset a distance above an upper surface of the wheeled base; and

,

a patient support structure, a portion of which is supported by the pedestal, the patient support structure being attached in a horizontally translatable relationship to the transport stretcher to allow the patient support structure to be movable into and out of the bore, and including a superior section and an inferior section, the inferior section being offset horizontally a distance from the superior section to define an opening therebetween, the inferior section being further connected to the superior section by arches lateral to, the opening of the patient support structure, wherein when the patient support is aligned on the transport stretcher, a portion of the patient support including the opening is projected from the pedestal to provide substantially unrestricted access to a body part of the patient retained in the patient support structure.

2. The apparatus of claim 1, wherein the arches connect the two sections together at lateral edges thereof.

3. The apparatus of claim 1, wherein the arches also curve inwardly to conform to the shape of the bore.

4. The apparatus of claim 3, wherein the arches connect together above the patient to form a generally semi-cylindrical structure.

5. The apparatus of claim 1, further including a compression device with compression plates attachable to and removable from the patient support structure when the patient is supported on the patient support structure.

6. The apparatus of claim 5, wherein the compression device includes multiple locking supports movable along linear guides in a medial-lateral direction for locking the compression plates in a desired position.

7. The apparatus of claim 5, wherein a compression plate comprises a fenestrated plate.

8. The apparatus of claim 5, wherein the compression plates are provided with at least one RF coil for MR imaging.

9. The apparatus of claim 8, wherein the compression plates are provided with at least one RE coil having a selected size corresponding to a size of body part being imaged.

10. The apparatus of claim 1, further including at least one RE coil attachable to and removable from the patient support structure when the patient is supported on the patient support structure.

11. The apparatus of claim 1, wherein the transport stretcher is dockable to the MR imaging system.

12. The apparatus of claim 1, wherein the transport stretcher includes a second pedestal and the portion of the patient support including the opening spans between the pedestal and the second pedestal.

13. The apparatus of claim 1, wherein the portion of the patient support structure including the opening is cantilevered from the pedestal.

14. The apparatus of claim 13, further including guides on the transport stretcher to constrain the movement of the patient support structure and prevent the patient support structure from tipping over.

15. The apparatus of claim 1, further including guides on the transport stretcher to constrain the movement of the patient support structure.

16. The apparatus of claim 1, further including a lighting device to provide illumination of the body part.

17. The apparatus of claim 1, wherein the inferior section of the patient support structure ramps up to the opening.

18. The apparatus of claim 17, wherein the superior section of the patient support structure ramps up to the opening.

19. The apparatus of claim 18, further including an adjustable headrest.

20. The apparatus of claim 1, further including a fluids barrier underneath the opening.

21. The apparatus of claim 1, wherein the portion of the patient support including the opening is projected over the upper surface of the wheeled base.

22. An apparatus used in conjunction with breast imaging and intervention for supporting a patient in a prone position and transporting the patient to an MR imaging system having a bore, the apparatus comprising:

a transport stretcher including a wheeled base and a pedestal supported on the wheeled base, an upper surface of the pedestal being offset a distance above an upper surface of the wheeled base; and

,

a patient support structure, a portion of which is supported by the pedestal the patient support structure being attached in a horizontally translatable relationship to the transport stretcher to allow the patient support structure to be movable into and out of the bore, and including a superior section and an inferior section, the inferior section being offset horizontally a distance from the superior section to define an opening therebetween sized to allow a breast to hang pendant through the opening, the inferior section being further connected to the superior section by arches lateral to, the opening of the patient support structure wherein when the patient support is aligned on the transport stretcher, a portion of the patient support including the opening is projected from the pedestal to allow medial and lateral and anterior access to the breast.

23. The apparatus of claim 22, further including a compression device with compression plates for immobilizing the breast which are attachable to and removable from the patient support structure when the patient is supported on the patient support structure.

24. The apparatus of claim 23, wherein the compression plates are configured to immobilize both of the patient'"'"'s breasts during bilateral imaging of the breasts.

25. The apparatus of claim 23, wherein the compression plates are provided with at least one RF coil for MR imaging.

26. The apparatus of claim 25, wherein the compression plates are provided with at least one RE coil having a selected size corresponding to a breast size being imaged.

27. The apparatus of claim 22, further including a removable sternum support member.

28. The apparatus of claim 22, further including a removable breast support for supporting a contra-lateral breast and compressing the contra-lateral breast.

29. The apparatus of claim 28, wherein the removable breast support is angled with respect to a horizontal plane.

30. The apparatus of claim 22, further including a mirror positioned such that an operator may see the nipple of the breast when positioning the patient.

31. The apparatus of claim 22, wherein the portion of the patient support including the opening is projected over the upper surface of the wheeled base.