Transdermal delivery system for dried particulate or lyophilized medications
First Claim
1. A printed patch comprising a non-adhesive liner and a dried pharmaceutical composition comprising parathyroid hormone (PTH) or a fragment thereof that can elevate calcium ions or decrease phosphorus in blood in a manner similar to that of PTH(1-34), with the PTH or fragment being present on the non-adhesive liner, wherein the non-adhesive liner is made of a material that is not permeable to PTH or the fragment thereof.
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Accused Products
Abstract
The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of an agent that generates hydrophilic micro-channels, and a patch comprising a therapeutically active agent. The present invention is useful for transdermal delivery of hydrophilic agents, particularly of high molecular weight proteins.
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Citations
28 Claims
- 1. A printed patch comprising a non-adhesive liner and a dried pharmaceutical composition comprising parathyroid hormone (PTH) or a fragment thereof that can elevate calcium ions or decrease phosphorus in blood in a manner similar to that of PTH(1-34), with the PTH or fragment being present on the non-adhesive liner, wherein the non-adhesive liner is made of a material that is not permeable to PTH or the fragment thereof.
Specification