Electrophoresis apparatus and a plate therefor
First Claim
1. A plate for housing a sieving matrix for electrophoresis of a sample, said plate including an optical waveguide array within the sieving matrix, said optical waveguide array being adapted to focus and/or refocus a laser beam, and being characterized by being aligned with respect to a reference direction such as to enable one or more laser beams incident on the sieving matrix along said reference direction to be maintained well-confined along said reference direction within any desired length of interaction along the width of said sieving matrix.
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Accused Products
Abstract
The invention provides an electrophoresis apparatus comprising an electrophoretic chamber containing at least on two-plate housing for a sieving matrix, each said at least one two-plate housing consisting of a cover plate and a plate for housing said sieving matrix, wherein said plate includes an optical waveguide array which is characterized by being aligned with respect to a reference direction such as to enable one or more light beams incident on the sieving matrix along said reference direction to be maintained well-confined along said reference direction within any desired length of interaction along the width of said sieving matrix.
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Citations
19 Claims
- 1. A plate for housing a sieving matrix for electrophoresis of a sample, said plate including an optical waveguide array within the sieving matrix, said optical waveguide array being adapted to focus and/or refocus a laser beam, and being characterized by being aligned with respect to a reference direction such as to enable one or more laser beams incident on the sieving matrix along said reference direction to be maintained well-confined along said reference direction within any desired length of interaction along the width of said sieving matrix.
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9. An electrophoresis apparatus comprising:
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(i) an electrophoretic chamber containing at least one two-plate housing for a sieving matrix, each said at least one two-plate housing consisting of a cover plate and a plate for housing said sieving matrix, wherein said plate includes an optical waveguide array within the sieving matrix, wherein said optical waveguide is adapted to refocus a laser beam and which is characterized by being aligned with respect to a reference direction such as to enable the laser beam incident on the sieving matrix along said reference direction to be maintained well-confined along said reference direction within any desired length of interaction along the width of said sieving matrix; (ii) at least one laser source; and (iii) at least one light detector. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17)
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18. A plate including a sieving matrix for electrophoresis of a sample,
said plate including an optical waveguide array extending in the width direction of the plate within the sieving matrix for focusing a laser beam, said optical waveguide array comprising a plurality of convex shaped lenses extending along said array, said array being characterized by being aligned with respect to a reference direction such as to enable the laser beam incident on the sieving matrix along said reference direction to be maintained focused and well-confined along said reference direction within any desired length of interaction along the width of said sieving matrix.
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19. A generally planar plate extending along x and y directions, wherein the x direction is the width direction, and the y direction is the length direction, said plate including a sieving matrix for electrophoresis of a sample,
said plate including an optical waveguide array within the sieving matrix having a plurality of gel lanes extending in the y direction, said optical waveguide array being aligned in the x direction such as to enable a laser beam incident on the sieving matrix along the x direction to be maintained focused and well-confined along said x direction within any desired length of interaction along the width of said sieving matrix.
Specification