Hybridization method and hybridization equipment
First Claim
1. Hybridization equipment comprising:
- a biochip prepared by fixing biopolymers to a plurality of sites on a biochip substrate,positive and negative electrodes for generating an electric field along the surface of said biochip substrate, anda magnetic field generating means for generating a magnetic field along the surface of said biochip substrate;
wherein the electric and magnetic fields generated by said electrodes and said magnetic field generating means simultaneously act along the surface of said biochip substrate to move said biopolymers along the surface of said biochip substrate in a fluid stored over said biochip substrate and to attract said biopolymers towards the surface of said biochip substrate during hybridization of said biopolymers,wherein said electric and magnetic fields are perpendicular to each other, andwherein said positive and negative electrodes are bow-shaped backwards against said sites.
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Abstract
The equipment of the present invention can implement high-speed hybridization with a simple construction and is configured as described below.
The equipment comprises a biochip prepared by fixing biopolymers onto a plurality of sites on a substrate, positive and negative electrodes for generating an electric field along the surface of this biochip substrate, and a magnetic field generating means for generating a magnetic field along the surface of the above biochip substrate, and is configured to move biopolymers movable in the fluid stored over the above-mentioned biochip substrate along the surface of the above biochip substrate as well as to attract the above described biopolymers towards the surface of the above biochip substrate during hybridization of the above biopolymers, by making the above-mentioned electric and magnetic fields act along the surface of the above biochip substrate.
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Citations
8 Claims
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1. Hybridization equipment comprising:
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a biochip prepared by fixing biopolymers to a plurality of sites on a biochip substrate, positive and negative electrodes for generating an electric field along the surface of said biochip substrate, and a magnetic field generating means for generating a magnetic field along the surface of said biochip substrate; wherein the electric and magnetic fields generated by said electrodes and said magnetic field generating means simultaneously act along the surface of said biochip substrate to move said biopolymers along the surface of said biochip substrate in a fluid stored over said biochip substrate and to attract said biopolymers towards the surface of said biochip substrate during hybridization of said biopolymers, wherein said electric and magnetic fields are perpendicular to each other, and wherein said positive and negative electrodes are bow-shaped backwards against said sites. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification