Treatment of bone disorders with skeletal anabolic drugs
First Claim
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1. A method of increasing bone mass in a human patient in need thereof, said method comprising administering intermittently to said patient PTHrP at a dosage of at least 500 μ
- g/day for a period of at least one month, wherein the bone mass density of said patient increases at a rate of at least 1% per month.
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Abstract
Disclosed herein are methods for the prevention and treatment of a variety of mammalian conditions manifested by loss of bone mass, including osteoporosis. The present invention provides methods of using PTHrP, or analogs thereof, for the treatment of metabolic bone disorders that are both effective and have an increased safety.
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10 Claims
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1. A method of increasing bone mass in a human patient in need thereof, said method comprising administering intermittently to said patient PTHrP at a dosage of at least 500 μ
- g/day for a period of at least one month, wherein the bone mass density of said patient increases at a rate of at least 1% per month.
- View Dependent Claims (2, 3, 4, 5)
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6. A method of treating a human patient afflicted with osteoporosis, said method comprising administering intermittently PTHrP to said patient at a dosage at least about 500 μ
- g/day for a period of 1-36 months, wherein the bone mass density of said patient increases at a rate of at least 1% per month.
- View Dependent Claims (7, 8, 9, 10)
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