Methods for treating valve-associated regions of vascular vessels
First Claim
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1. A method for treating a vein in a patient, said method comprising:
- accessing a treatment site proximate to a valve in the vein,introducing a remodelable biomaterial into, or in contact with an exterior surface of, a wall of the vein at the treatment site, andwherein said remodelable biomaterial is effective to shrink as a result of remodeling so as to reshape the vein.
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Abstract
This invention relates in one aspect to the treatment of a valve-associated region of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
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Citations
50 Claims
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1. A method for treating a vein in a patient, said method comprising:
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accessing a treatment site proximate to a valve in the vein, introducing a remodelable biomaterial into, or in contact with an exterior surface of, a wall of the vein at the treatment site, and wherein said remodelable biomaterial is effective to shrink as a result of remodeling so as to reshape the vein. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method of treating a vein of a patient, said method comprising:
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accessing a treatment site along the vein, said treatment site proximate to a valve within the vein; and introducing a flowable mass of biocompatible material in contact with an exterior surface of a wall of the vein at said treatment site. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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- 27. A method for treating a vascular vessel in a patient, comprising introducing a remodelable biomaterial into, or in contact with an exterior surface of, a wall of the vessel in a region proximate to a vascular valve in the vessel, wherein said remodelable biomaterial is effective to shrink as a result of remodeling so as to re-shape the vessel.
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43. A method for treating a patient having an insufficient vascular valve, said method comprising:
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establishing percutaneous access to a vascular vessel of a patient; treating a native vascular valve and/or introducing an artificial vascular valve in a vascular vessel of the patient through the percutaneous access; and reinforcing the vascular vessel in a region proximate to said native vascular valve or artificial vascular valve by implanting a biocompatible material into a wall of the vessel or in contact with an exterior surface of a wall of the vessel. - View Dependent Claims (44, 45, 46, 47, 48, 49, 50)
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Specification