Nanotechnology for biomedical implants
First Claim
Patent Images
1. A biomedical implant nanocomposite comprising:
- a matrix;
nanofillers comprising one or more elements selected from the group consisting of;
aluminum, barium, bismuth, calcium, cerium, copper, dysprosium, europium, gadolinium, hafnium, indium, lanthanum, magnesium, neodymium, niobium, prascodymium, silver, strontium, tantalum, tin, tungsten, ytterbium, yttrium, zinc, and zirconium;
wherein the nanofillers comprise an oxide ceramic or a hydroxide;
wherein the nanofillers comprise a domain size less than 50 nanometers and are mixed into the matrix at a loading of less than 80 volume percent;
wherein the mixed nanofillers and matrix are formed into a solid nanocomposite biomedical implant;
wherein the solid nanocomposite biomedical implant exhibits a wear resistance that differs by more than 20% as compared with the wear resistance exhibited by a composite comprising micron scale filler of a composition substantially same as the nanofiller, andwherein the nanofillers comprise a surface consisting of a thin layer of a phase that is compatible with the matrix composition.
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Abstract
Biomedical nanocomposite implants having both low-loaded and highly-loaded nanocomposites. A matrix and nanofillers are provided wherein the nanofillers are dispersed in the matrix to form a composite. Nanoscale coated and un-coated fillers are used. Methods for preparing biomedical nanocomposite implants are also illustrated.
27 Citations
23 Claims
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1. A biomedical implant nanocomposite comprising:
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a matrix; nanofillers comprising one or more elements selected from the group consisting of;
aluminum, barium, bismuth, calcium, cerium, copper, dysprosium, europium, gadolinium, hafnium, indium, lanthanum, magnesium, neodymium, niobium, prascodymium, silver, strontium, tantalum, tin, tungsten, ytterbium, yttrium, zinc, and zirconium;wherein the nanofillers comprise an oxide ceramic or a hydroxide; wherein the nanofillers comprise a domain size less than 50 nanometers and are mixed into the matrix at a loading of less than 80 volume percent; wherein the mixed nanofillers and matrix are formed into a solid nanocomposite biomedical implant; wherein the solid nanocomposite biomedical implant exhibits a wear resistance that differs by more than 20% as compared with the wear resistance exhibited by a composite comprising micron scale filler of a composition substantially same as the nanofiller, and wherein the nanofillers comprise a surface consisting of a thin layer of a phase that is compatible with the matrix composition. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A biomedical implant comprising:
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a matrix; nanofillers comprising two or more elements selected from the group consisting of;
aluminum, barium, bismuth, calcium, cerium, cesium, cobalt, copper, dysprosium, erbium, europium, gadolinium, gallium, gold, hafnium, indium, iridium, lanthanum, lithium, magnesium, manganese, mendelevium, mercury, molybdenum, neodymium, neptunium, nickel, niobium, osmium, palladium, platinum, potassium, praseodymium, promethium, protactinium, rhenium, rubidium, scandium, silver, sodium, strontium, tantalum, terbium, thallium, thorium, tin, titanium, tungsten, vanadium, ytterbium, yttrium, zinc and zirconium;wherein the nanofillers comprise an oxide ceramic or a hydroxide; wherein the nanofillers comprise a domain size less than 50 nanometers and are mixed into the matrix at a loading of less than 80 volume percent; wherein the mixed nanofillers and matrix are formed into a solid nanocomposite biomedical implant; wherein the solid nanocomposite biomedical implant exhibits a wear resistance that differs by more than 20% as compared with the wear resistance exhibited by a composite implant comprising of micron scale filler of a composition substantially same as the nanofiller, and wherein the nanofillers comprise a surface consisting of a thin layer or a phase that is compatible with the matrix composition. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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15. A biomedical implant comprising:
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a matrix; coated nanofillers comprising one or more elements selected from the group consisting of;
aluminum, barium, bismuth, calcium, cerium, cesium, cobalt, copper, dysprosium, erbium, europium, gadolinium, gallium, gold, hafnium, indium, iridium, lanthanum, lithium, magnesium, manganese, mendelevium, mercury, molybdenum, neodymium, neptunium, nickel, niobium, osmium, palladium, platinum, potassium, praseodymium, promethium, protactinium, rhenium, rubidium, scandium, silver, sodium, strontium, tantalum, terbium, thallium, thorium, tin, titanium, lungsten, vanadium, ytterbium, yttrium, zinc and zirconium;wherein the nanofillers comprise an oxide ceramic or a hydroxide; wherein the coated nanofillers comprise a domain size less than 50 nanometers and are mixed into the matrix at a loading of less than 80 volume percent; wherein the mixed coated nanofillers and matrix are formed into a solid nanocomposite biomedical implant; and wherein the solid nanocomposite biomedical implant exhibits a wear resistance that differs by more than 20% as compared with the wear resistance exhibited by a composite implant comprising of micron scale filler of a composition substantially same as the nanofiller. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23)
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Specification