Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor

• US 7,388,110 B2
• Filed: 07/25/2005
• Issued: 06/17/2008
• Est. Priority Date: 07/23/2004
• Status: Active Grant

• Current Assignee: Terumo Kabushiki Kaisha (Terumo Corporation)
• Original Assignee: Terumo Kabushiki Kaisha (Terumo Corporation)
• Inventors: Ochiai, Shouji, Matsumoto, Atsushi, Kawanishi, Tetsuro
• Primary Examiner(s): Eyler; Yvonne (Bonnie)
• Assistant Examiner(s): Nwaonicha; Chukwuma O.
• Application Number:
  US11/187,821
• Publication Number:
  US 20060020182A1
• Time in Patent Office: 1,058 Days
• Field of Search: 600/315, 562/7, 564/8
• US Class Current: 564/8
• CPC Class Codes: C07F 5/025 Boronic and borinic acid compounds
• CPC Class Codes: C09K 11/06 containing organic luminescent materials
• CPC Class Codes: C09K 2211/1007 Non-condensed systems
• CPC Class Codes: C09K 2211/1011 Condensed systems
• CPC Class Codes: C09K 2211/1014 bridged by heteroatoms, e.g. N, P, Si or B

Abstract

A fluorescent monomer compound represented by the following formula (1) is provided:

wherein Q, Q′ and D³ may be the same or different, may be combined together into a fused ring, and are each a substituent selected from the group consisting of a hydrogen atom, a halogen atom, a hydroxyl group, and substituted or unsubstituted alkyl, acyl, oxyalkyl, carboxyl, carboxylate ester, carboxamido, cyano, nitro, amino and aminoalkyl groups; and D¹, D² and D⁴ each represent a substituent, wherein at least one of D¹, D² and D⁴ is a substituent group comprising a vinyl group at an end thereof, and wherein the substituent group comprising a vinyl group at an end thereof enables the fluorescent monomer compound to be soluble in water.

Claims

1. A fluorescent monomer compound represented by the following formula (1):

2. A fluorescent monomer compound represented by the following formula (1):

3. The fluorescent monomer compound according to claim 2, wherein said substituent group represented by the formula (2) or said substituent group represented by the formula (3) enables the fluorescent monomer compound to be soluble in water.

4. The fluorescent monomer compound according to claim 2, wherein D₁, D₂, D₃ and D₄ have the meanings as defined under the definition (i), and Y is a substituted or unsubstituted, linear, divalent, organic residual group having a number of atoms of from 3 to 500.