Contrast-enhanced cone beam X-ray imaging, evaluation, monitoring and treatment delivery
First Claim
1. A method of imaging a patient'"'"'s uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprising the steps of introducing an effective amount of a contrast agent to the uncompressed region of interest, and acquiring a plurality of projection images for a tomography data set of the uncompressed region of interest according to the following equation:
-
Δ
t≦
Δ
x/v where v represents a velocity that the uncompressed region of interest moves during the acquisition, Δ
x represents a spatial resolution of the tomography data set, and Δ
t represents a time interval acquiring the tomography data set.
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Accused Products
Abstract
A method of imaging a patient'"'"'s uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient'"'"'s uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.
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Citations
30 Claims
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1. A method of imaging a patient'"'"'s uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprising the steps of introducing an effective amount of a contrast agent to the uncompressed region of interest, and acquiring a plurality of projection images for a tomography data set of the uncompressed region of interest according to the following equation:
-
Δ
t≦
Δ
x/vwhere v represents a velocity that the uncompressed region of interest moves during the acquisition, Δ
x represents a spatial resolution of the tomography data set, and Δ
t represents a time interval acquiring the tomography data set.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method of imaging a patient'"'"'s uncompressed region of interest using X-ray cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprising the step of acquiring a plurality of two-dimensional projection images for a CBCT or CBDT data set at a rate of at least 1000 images per second, in which the CBCT or CBDT data set is acquired according to the following equation:
-
Δ
t≦
Δ
x/vwhere v represents a velocity that the uncompressed region of interest moves during the acquisition, Δ
x represents a spatial resolution of the tomography data set, and Δ
t represents a time interval acquiring the tomography data set.
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23. A method of imaging a patient'"'"'s uncompressed region of interest using X-ray cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprising the step of generating a three-dimensional computed tomography image data set of the uncompressed region of interest resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions, according to the following equation:
-
Δ
t≦
Δ
x/vwhere Δ
t represents a time interval acquiring the tomography data set, and v represents a velocity that the uncompressed region of interest moves during the acquisition.- View Dependent Claims (24, 25)
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26. A method of delivering X-ray treatment dose distribution to a patient'"'"'s uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography, comprising the steps of introducing an effective amount of a contrast agent to the uncompressed region of interest, acquiring a plurality of two-dimensional projection images for a cone beam tomography data set and delivering an X-ray treatment dose distribution ranging from 1 to 7000 centigray to the uncompressed region of interest,
in which the tomography data set is acquired according to the following equation: -
Δ
t≦
Δ
x/vwhere v represents a velocity that the uncompressed region of interest moves during the aquisition, Δ
x represents a spatial resolution of the tomography data set, and Δ
t represents a time interval acquiring the tomography data set. - View Dependent Claims (27, 28, 29, 30)
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Specification