Detection of renal failure by cardiac implantable medical device
First Claim
1. A method of detecting renal failure comprising:
- tracking intervals between QRS-complexes and ends of corresponding T-waves (QTend intervals), intervals between QRS-complexes and peaks of corresponding T-waves (QTmax intervals) and elevations of a segment of a cardiac signal between QRS-complexes and corresponding T-waves (ST segment elevations), within electrical cardiac signals obtained using an implantable medical device; and
detecting renal failure, as opposed to myocardial ischemia, hypoglycemia or hyperglycemia when there is a deviation in ST segment elevation in combination with a decrease in QTend interval and a decrease in QTmax interval.
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Accused Products
Abstract
Morphological features within electrical cardiac signals are tracked and changes in features are monitored to detect renal failure. The morphological feature may be an interval between corresponding polarization events such as the interval between QRS-complexes and peaks of corresponding T-waves (QTmax interval); the interval between QRS-complexes and ends of corresponding T-waves (QTend interval); or the interval between P-waves and corresponding QRS-complexes (PR interval). The feature may also be the elevation of a cardiac signal segment between corresponding polarization events, such as QRS-complexes and corresponding T-waves (ST segment); a duration of a polarization event, such as a QRS-complex (QRS width); or an amplitude of a polarization event, such as a T-wave (T-wave amplitude). The change in the feature may comprise a decrease in QTmax intervals, a decrease in QTend intervals, a deviation in ST segment elevation, an increase in QRS width, an increase in PR interval or a deviation in T-wave amplitude.
19 Citations
11 Claims
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1. A method of detecting renal failure comprising:
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tracking intervals between QRS-complexes and ends of corresponding T-waves (QTend intervals), intervals between QRS-complexes and peaks of corresponding T-waves (QTmax intervals) and elevations of a segment of a cardiac signal between QRS-complexes and corresponding T-waves (ST segment elevations), within electrical cardiac signals obtained using an implantable medical device; and detecting renal failure, as opposed to myocardial ischemia, hypoglycemia or hyperglycemia when there is a deviation in ST segment elevation in combination with a decrease in QTend interval and a decrease in QTmax interval.
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2. A method of detecting renal failure comprising:
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for each of at least two different PQRST complexes within an intracardiac electrogram obtained using an implantable medical device, tracking two different intervals between QRS complexes and corresponding T waves; and detecting renal failure if each of the two different intervals decrease by a respective amount. - View Dependent Claims (3, 4, 5, 6)
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7. A method of detecting renal failure comprising:
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for each of at least two different PQRST complexes within an intracardiac electrogram obtained using an implantable medical device, tracking two different intervals between QRS complexes and corresponding T waves and tracking another morphological feature within the two different PQRST complexes; and detecting renal failure if each of the two different intervals decrease by a respective amount and the other morphological feature changes. - View Dependent Claims (8, 9, 10, 11)
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Specification