Injection apparatus for delivering therapeutic

• US 7,402,155 B2
• Filed: 02/22/2002
• Issued: 07/22/2008
• Est. Priority Date: 12/08/1999
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Palasis, Maria, Rosenthal, Arthur
• Primary Examiner(s): Mendez; Manuel
• Application Number:
  US10/079,505
• Publication Number:
  US 20020095124A1
• Time in Patent Office: 2,342 Days
• Field of Search: 604/164.01, 604/164.02, 604/164.03, 604/164.04, 604/164.06, 604/164.11, 604/171, 604/173, 604/176, 604/523, 604/264, 604/272, 606/167, 606/170
• US Class Current: 604/272
• CPC Class Codes: A61B 17/32037 for removing obstructions from inner organs or blood vessels, e.g. for atherectomy
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61M 2025/0089 Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0084 being one or more injection needles
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/3291 Shafts with additional lateral openings

Abstract

A catheter for delivering therapeutic to an injection site within the body is provided. This catheter can include a shaft having a proximal end, a distal end, and an infusion lumen extending therein; a penetrating member coupled to the shaft and extendable from the distal end of the shaft, and a stabilizer positioned towards the distal end of the shaft. The catheter could also include a delivery system, able to be calibrated to deliver therapeutic through an injection port at a rate less than the therapeutic absorption rate of the injection site.

Claims

1. A catheter for delivering therapeutic to an injection site within the body, comprising:

a shaft having a proximal end, a distal end, and an infusion lumen extending therein;

a penetrating member coupled to the shaft and extendable from the distal end of the shaft, the penetrating member having an injection port and a piercing tip, wherein the penetrating member penetrates the injection site in a first direction, and wherein the injection port directs therapeutic in a second direction different from the first direction; and

a stabilizer positioned towards the distal end of the shaft, wherein the stabilizer is adapted to maintain the distal end of the shaft against the injection site while the penetrating member penetrates the injection site.

2. The catheter of claim 1 wherein the stabilizer comprises a suction head.

3. The catheter of claim 2 wherein the suction head is coupled to a suction lumen.

4. The catheter of claim 1 further comprising:

a therapeutic delivery system, the system adjustable to deliver therapeutic through the injection port at various pre-selected pressure ranges.

5. The catheter of claim 4 wherein the delivery system includes a therapeutic vessel and wherein the delivery system is adjusted to deliver therapeutic through the injection port at a pressure of less than one atmosphere.

6. The catheter of claim 4 wherein the delivery system includes a therapeutic vessel and wherein the delivery system is adjusted to deliver therapeutic through the injection port at a pressure of greater than one atmosphere.

7. The catheter of claim 4 wherein the delivery system is adjusted to deliver therapeutic at a rate less than the therapeutic absorption rate of the injection site.

8. The catheter of claim 1 wherein said second direction is at an angle non-orthogonal and non-parallel to the first direction.

9. The catheter of claim 1 wherein the penetrating member has a plurality of injection ports that direct therapeutic in a direction different from the first direction.

10. A catheter for delivering therapeutic to an injection site within the body, comprising:

a shaft having a proximal end, a distal end, and an infusion lumen extending therein;

a penetrating member coupled to the shaft and extendable from the distal end of the shaft,

the penetrating member having an injection port and a piercing tip, wherein the penetrating member penetrates the injection site in a first direction, and wherein the injection port directs therapeutic in a second direction different from the first direction; and

a delivery system,

the delivery system able to be calibrated to deliver therapeutic through the injection port at a rate less than the therapeutic absorption rate of the injection site.

11. The catheter of claim 10 further comprising:

a stabilizer positioned towards the distal end of the shaft.

12. The catheter of claim 11 wherein the stabilizer comprises a suction head.

13. The catheter of claim 12 wherein the suction head is coupled to a suction lumen.

14. The catheter of claim 11 wherein the stabilizer comprises a forceps.

15. The catheter of claim 11 wherein the stabilizer comprises a penetrating anchor.

16. The catheter of claim 10 wherein the delivery system includes a therapeutic vessel and wherein the delivery system is calibrated to deliver therapeutic through the injection port at a pressure of less than one atmosphere.

17. The catheter of claim 10 wherein the delivery system includes a therapeutic vessel and wherein the delivery system is calibrated to deliver therapeutic through the injection port at a pressure of greater than one atmosphere.

18. The catheter of claim 10 wherein said second direction is at an angle non-orthogonal and non-parallel to the first direction.

19. The catheter of claim 10 wherein the penetrating member has a plurality of injection ports that direct therapeutic in a direction different from the first direction.

20. A catheter injection system for delivering therapeutic to an injection site within the body, comprising:

a shaft having a proximal end, a distal end, and an infusion lumen extending therein;

a penetrating member coupled to the shaft and extendable from the distal end of the shaft, the penetrating member having an injection port and a piercing tip; and

a stabilizer for maintaining the distal end of the shaft in a relatively fixed position while the penetrating member penetrates the injection site;

wherein the penetrating member penetrates the injection site in a first direction, and wherein the injection port directs therapeutic in a second direction different from the first direction, said second direction is at an angle non-orthogonal and non-parallel to the first direction such that therapeutic leakage from the injection site is reduced.