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Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method

  • US 7,402,381 B2
  • Filed: 08/27/2004
  • Issued: 07/22/2008
  • Est. Priority Date: 09/11/2003
  • Status: Expired due to Fees
First Claim
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1. A method of immobilization, comprising:

  • immobilizing a plurality of first molecules and a plurality of second molecules to a solid phase substrate by putting a solution of the plurality of first and second molecules in contact with the solid phase substrate,each of the plurality of first molecules having a first functional portion that is used for recognizing a first object to be examined,each of the plurality of first molecules including a first joint portion, the first functional portion being immobilized through the first joint portion that is capable of binding to the solid phase substrate,each of the plurality of second molecules having a second functional portion that is different from the first functional portion and that functions as a mediator of the first functional portion, andeach of the plurality of second molecules including a second joint portion, the second functional portion being immobilized through the second joint portion that is capable of binding to the solid phase substrate.

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