Method and implantable systems for neural sensing and nerve stimulation

• US 7,403,821 B2
• Filed: 02/16/2001
• Issued: 07/22/2008
• Est. Priority Date: 02/17/2000
• Status: Expired due to Fees

• Current Assignee: Neurodan AS
• Original Assignee: Neurodan AS
• Inventors: Sinkjaer, Thomas, Haugland, Morton
• Primary Examiner(s): Sykes; Angela D.
• Assistant Examiner(s): ALTER, ALYSSA MARGO
• Application Number:
  US10/203,908
• Publication Number:
  US 20030144710A1
• Time in Patent Office: 2,713 Days
• Field of Search: 607/48, 607/49, 607/144, 607/46, 607/148
• US Class Current: 607/49
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/1038 Measuring plantar pressure during gait
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/4052 efferent nerves, i.e. nerves that relay impulses from the central nervous system
• CPC Class Codes: A61B 5/4519 Muscles A61B5/389, A61B5/224 take precedence
• CPC Class Codes: A61B 5/4528 Joints A61B5/4533, A61B5/4538 take precedence
• CPC Class Codes: A61B 5/7217 of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
• CPC Class Codes: A61F 2/72 Bioelectric control, e.g. myoelectric
• CPC Class Codes: A61F 2002/704 computer-controlled, e.g. robotic control
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance

Abstract

The present invention relates to methods and apparatuses for the detection of neural or muscular activity, analysis of the signals and the subsequent stimulating of neural or muscular tissue based thereon. According to a first aspect of the invention an apparatus for producing a muscular action is provided, comprising a combined sensing and stimulation electrode device comprising at least one neurosense electrode means capable of sensing a nerve signal from a peripheral nerve and at least one stimulation electrode means capable of stimulating a peripheral motor nerve fiber, means for receiving and processing the sensed neurosignals to identify a signal indicative of a specific action, especially a component of the gait performed by the patient and for producing a control signal in response thereto, and means for operating the at least one stimulation electrode means in response to the control signal to produce a stimulation of a peripheral motor nerve fiber.

Claims

1. A method of producing a dorsiflexion of a foot of a patient, the method comprising:

arranging sensing and stimulation electrodes on at least one peripheral upper leg nerve above a knee of the patient, said at least one peripheral upper leg nerve having sensor nerve fibres innervating portions of the lower leg of the patient and motor nerve fibres innervating musculature of the lower leg;

sensing neurosignals from the sensor nerve fibres via the sensing electrode,

processing the sensed neurosignals to detect an action indicative of the timing of heel strike and heel lift of the patient, and

operating the stimulation electrode in response to the detected action to produce the dorsiflexion of the foot of the patient.

2. The method of claim 1, wherein said arranging sensing and stimulation electrodes comprises providing a plurality of individual neurosense electrodes and a plurality of individual stimulation electrodes, wherein the processed neurosignals are selected from one or more of the plurality of individual neurosense electrodes, and wherein one or more of the plurality of individual stimulation electrodes is operated in response hereto.

3. The method of claim 1, wherein said arranging sensing and stimulation electrodes comprises providing a combined sensing and stimulation electrode device having least one combined electrode,

wherein the method further comprises switching each combined electrode between a neurosense electrode state and a stimulation electrode state.

4. A method of producing a dorsiflexion of a foot of a patient in response to a detection of an action indicative of a timing of a heel strike and a heel lift of the patient, the method comprising:

providing a sensing and stimulation electrode device comprising at least one neurosense electrode capable of sensing a nerve signal from a peripheral nerve and at least one stimulation electrode capable of stimulating a peripheral motor nerve fibre,

arranging the sensing and stimulation electrodes on at least one peripheral upper leg nerve proximal to a knee of the patient, the nerve comprising sensor nerve fibres innervating portions of the lower leg of the patient and motor nerve fibres innervating musculature of the lower leg,

receiving and processing the sensed neurosignals to identify an action indicative of the timing of heel strike and heel lift of the patient and producing a control signal in response thereto, and

operating the at least one stimulation electrode in response to the control signal to produce a stimulation of a peripheral motor nerve fibre so as to produce the dorsiflexion of the foot of the patient.

5. The method of claim 4, wherein said providing a sensing and stimulation electrode device comprises providing a plurality of individual neurosense electrodes and a plurality of individual stimulation electrodes,

wherein said receiving and processing further comprises selecting signals from at least one of the plurality of individual neurosense electrodes, and wherein at least one of the plurality of individual stimulation electrodes is operated in response thereto.

6. The method of claim 4, wherein said providing a sensing and stimulation electrode device comprises providing a combined sensing and stimulation electrode device having at least one combined electrode,

wherein the method further comprises switching each combined electrode between a neurosense electrode state and a stimulation electrode state.

7. A method of operating a stimulation electrode, the method comprising:

arranging the stimulation electrode on a peripheral upper leg nerve above a knee of a patient, the nerve comprising nerve fibre innervating musculature on a lower leg below the knee,

detecting an action indicative of the timing of heel strike and heel lift of the patient, and

operating the stimulation electrode in response to the detected action to produce a dorsiflexion of a foot of the patient.

8. A method as defined in claim 7, wherein the stimulation electrode is a multi-channel electrode comprising a plurality of individual electrodes.

9. A method as defined in claim 7, wherein the stimulation electrode is activated through a signal transmitted through the skin of a patient.

10. A method of producing a dorsiflexion of a foot of a patient in response to a detection of an action indicative of a timing of a heel strike and a heel lift of the patient, the method comprising:

detecting an action indicative of the timing of the heel strike and the heel lift of the patient,

providing a stimulation electrode,

arranging the stimulation electrode on a peripheral upper leg nerve proximal to a knee of the patient, the nerve being the peroneal nerve, the nerve comprising nerve fibres innervating musculature on the lower leg capable of producing the dorsiflexion of the foot, and

operating the stimulation electrode to produce the dorsiflexion of the foot in response to a detected action.