Antimicrobial lenses, processes to prepare them and methods of their use
First Claim
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1. A packaging solution for packaging an ophthalmic device comprising at least one antimicrobial metal salt having a Ksp of less than about 10−
- 10 wherein said solution has an osmolality of about 220 mOsm/kg or greater and is substantially free from packaging solution salts which have anions which when combined with a cation from said antimicrobial metal salt form a second salt, such that said ophthalmic device loses less than about 30% by weight of said antimicrobial metal salt during autoclaving and storage in said packaging solution.
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Abstract
This invention relates to solutions for packaging ophthalmic devices comprising at least one antimicrobial metal salt which prevent the loss of said antimicrobial metal salt during autoclaving and storage.
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Citations
11 Claims
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1. A packaging solution for packaging an ophthalmic device comprising at least one antimicrobial metal salt having a Ksp of less than about 10−
- 10 wherein said solution has an osmolality of about 220 mOsm/kg or greater and is substantially free from packaging solution salts which have anions which when combined with a cation from said antimicrobial metal salt form a second salt, such that said ophthalmic device loses less than about 30% by weight of said antimicrobial metal salt during autoclaving and storage in said packaging solution.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A packaging solution for packaging an ophthalmic device comprising at least one antimicrobial metal salt having a Ksp of less than about 10−
- 10 wherein said solution has an osmolality of about 220 mOsm/kg or greater and is substantially free from packaging solution salts which have anions which when combined with a cation from said antimicrobial metal form a salt having a Ksp which is less than about six orders of magnitude less that said Ksp of said antimicrobial metal salt and said antimicrobial metal salt is present in a concentration sufficient to provide loss of said antimicrobial metal salt from said ophthalmic device upon autoclaving of less than about 15%.
Specification